CCDC93 (NM_019044) Human Untagged Clone

SKU SC113308

CCDC93 (untagged)-Human coiled-coil domain containing 93 (CCDC93)

Product Data

• Type: Human Untagged Clone
• Target Symbol: CCDC93
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_019044, the custom clone sequence may differ by one or more nucleotides; ; ; ATGGGGTTGCCCAGGGGGCCGGAGGGCCAGGGTCTCCCGGAGGTGGAAACAAGAGAAGATGAAGAACAAA; ATGTCAAGTTGACTGAAATTCTGGAGCTCTTGGTTGCAGCTGGGTATTTCAGGGCAAGAATTAAAGGCTT; ATCACCCTTTGACAAGGTAGTAGGAGGAATGACTTGGTGTATCACCACTTGCAACTTTGATGTAGATGTT; GATTTGCTCTTTCAAGAAAACTCTACGATAGGTCAAAAAATAGCTCTGTCAGAAAAAATTGTCTCGGTCC; TGCCAAGGATGAAATGCCCACACCAGCTGGAGCCCCACCAGATCCAGGGGATGGATTTTATTCACATATT; TCCTGTTGTTCAGTGGCTGGTGAAACGAGCTATAGAAACAAAAGAAGAGATGGGTGACTATATCCGCTCC; TACTCTGTATCCCAGTTCCAGAAGACTTACAGTCTCCCTGAGGATGATGACTTCATAAAGAGAAAAGAAA; AGGCCATCAAGACAGTTGTGGACCTCTCAGAAGTGTACAAGCCCCGTCGGAAATACAAACGCCACCAGGG; AGCAGAGGAGCTACTTGATGAAGAATCTCGAATCCATGCTACACTTTTGGAATATGGCAGGAGATATGGA; TTTAGCCGCCAGAGCAAAATGGAGAAGGCTGAGGACAAGAAAACGGCACTTCCAGCAGGGCTGTCAGCTA; CAGAAAAAGCTGATGCCCACGAGGAAGATGAGCTTCGAGCAGCTGAAGAGCAGCGTATTCAGTCGCTGAT; GACCAAGATGACCGCTATGGCAAATGAGGAGAGCCGTCTCACCGCAAGCTCCGTGGGCCAGATTGTGGGA; CTCTGCTCTGCTGAGATCAAGCAGATTGTGTCCGAGTATGCAGAGAAGCAGTCTGAGCTATCAGCTGAAG; AAAGTCCAGAAAAATTAGGAACCTCCCAGCTACATCGCCGGAAAGTCATTTCCTTGAACAAACAGATTGC; GCAAAAGACCAAACATCTTGAAGAGCTGCGAGCAAGTCACACCAGCCTACAAGCCAGATATAATGAAGCC; AAGAAAACGCTGACAGAGCTGAAGACTTACAGTGAGAAACTGGACAAAGAGCAAGCAGCCCTCGAGAAGA; TAGAATCCAAAGCTGATCCAAGTATCCTACAGAACCTGAGAGCACTTGTAGCCATGAATGAAAATCTGAA; AAGTCAAGAACAGGAATTTAAAGCACATTGTCGAGAGGAGATGACACGACTACAGCAAGAAATTGAAAAC; CTGAAAGCTGAGAGAGCACCACGTGGAGATGAAAAGACCCTCTCCAGTGGAGAGCCGCCTGGTACCTTGA; CCTCTGCAATGACTCATGACGAAGACCTAGACAGACGGTATAATATGGAGAAAGAGAAACTTTACAAGAT; ACGTTTACTACAGGCTCGAAGAAATCGAGAAATAGCAATTTTGCACCGCAAGATTGATGAAGTCCCTAGC; CGTGCCGAGCTAATACAGTATCAGAAGAGATTTATTGAACTCTACCGCCAGATTTCAGCAGTGCACAAAG; AAACCAAGCAGTTCTTCACTTTATATAATACCCTGGATGATAAAAAGGTTTATTTGGAAAAAGAGATTAG; TCTGCTGAACTCAATTCATGAGAACTTCTCACAGGCCATGGCCTCCCCTGCTGCCCGGGACCAGTTTTTA; CGTCAGATGGAACAGATTGTGGAAGGAATTAAGCAAAGTAGAATGAAGATGGAAAAGAAAAAGCAAGAGA; ACAAAATGAGAAGAGACCAGTTGAACGACCAGTACTTGGAGCTGTTAGAAAAGCAGAGGCTATACTTTAA; GACTGTGAAAGAGTTCAAGGAGGAGGGCCGCAAGAACGAGATGCTGCTGTCCAAGGTGAAAGCGAAGGCC; TCCTGA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_019044 unedited; ATAGGCGGGCCGCGAATTCGCACGAGGCCGGAAAGTCATTTCCTTGAACAAACAGATTGC; GCAAAAGACCAAACATCTTGAAGAGCTGCGAGCAAGTCACACCAGCCTACAAGCCAGATA; TAATGAAGCCAAGAAAACGCTGACAGAGCTGAAGACTTACAGTGAGAAACTGGACAAAGA; GCAAGCAGCCCTCGAGAAGATAGAATCCAAAGCTGATCCAAGTATCCTACAGAACCTGAG; AGCACTTGTAGCCATGAATGAAAATCTGAAAAGTCAAGAACAGGAATTTAAAGCACTGTC; GAGAGGAGATGACACGACTACAGCAAGAAATTGAAAACCTGAAAGCTGAGAGAGCACCAC; GTGGAGATGAAAAGACCCTCTCCAGTGGAGAGCCGCCTGGTACCTTGACCTCTGCAATGA; CTCATGACGAAGACCTAGACAGACGGTATAATATGGAGAAAGAGAAACTTTACAAGATAC; GTTTACTACAGGCTCGAAGAAATCGAGAAATAGCAATTTTGCACCGCAAGATTGATGAAG; TCCCTAGCCGTGCCGAGCTAATACAGTATCAGAAGAGATTTATTGAACTCTACCGCCAGA; TTTCAGCAGTGCACANAGAAACCAAGCAGTTCTTCACTTTATATAATACCCCTGGATGAT; AAAAAGGTTTATTTGGAAAAAGAGATTAGTCTGCTGAAACTCATTATGAGAACTTCTACA; GTNAGTACTGTCAAGTCTTCTTTCCACTATACCCTGCCGGNCTGCGCTTTGATTCAGCCC; ACTCACATGCTATANTGTGCTTTGACAAGTACATGCAGACTTACACTGGGTATGNGATTC; TACTCTTTAGCCTTCTGCTAGATCTTGTTAACCTCTCTTGGGTCTGCAACTTTAGGTTNN; AAGTGAAGGAAACTGCCAAAAGTTACTTCAAACTTTGCGGGCCCACTCTAAATTTTGGTG; TTATAATAAATTGGTATGAACAAAGAGCTTAATTACTAGGATTTTA;
• Restriction Sites: NotI-NotI
• ACCN: NM_019044
• Insert Size: 4840 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_019044.2, NP_061917.2
• RefSeq Size: 6946 bp
• RefSeq ORF: 1728 bp
• Locus ID: 54520
• UniProt ID: Q567U6
• Cytogenetics: 2q14.1
• Summary: Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1 (PubMed:28892079, PubMed:25355947). Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C (PubMed:25355947).[UniProtKB/Swiss-Prot Function]