CTPS2 (NM_019857) Human Untagged Clone
$546.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | CTPS2 |
| Synonyms | GATD5B |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_019857 |
| Insert Size | 2440 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_019857.3, NP_062831.3 |
| RefSeq Size | 3844 bp |
| RefSeq ORF | 1761 bp |
| Locus ID | 56474 |
| UniProt ID | Q9NRF8 |
| Cytogenetics | Xp22.2 |
| Domains | GATase |
| Protein Pathways | Metabolic pathways, Pyrimidine metabolism |
| Summary | The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2013 Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 2 and 3 encode the same protein. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_019857" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC205993 | CTPS2 (Myc-DDK-tagged)-Human CTP synthase II (CTPS2), transcript variant 1 | 10 ug |
$545.00
|
|
| RC205993L3 | Lenti ORF clone of Human CTP synthase II (CTPS2), transcript variant 1, Myc-DDK-tagged | 10 ug |
$845.00
|
|
| RC205993L4 | Lenti ORF clone of Human CTP synthase II (CTPS2), transcript variant 1, mGFP tagged | 10 ug |
$845.00
|
|
| RG205993 | CTPS2 (tGFP-tagged) - Human CTP synthase II (CTPS2), transcript variant 1 | 10 ug |
$489.00
$745.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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