DAB1 (NM_021080) Human Untagged Clone

SKU SC113027

DAB1 (untagged)-Human disabled homolog 1 (Drosophila) (DAB1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: DAB1
• Synonyms: SCA37
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113027 sequence for NM_021080 edited (data generated by NextGen Sequencing); ATGTCAACTGAGACAGAACTTCAAGTAGCTGTGAAAACCAGCGCCAAGAAAGACTCCAGA; AAGAAAGGTCAGGATCGCAGTGAAGCCACTTTGATAAAGAGGTTTAAAGGTGAAGGGGTC; CGGTACAAAGCCAAATTGATCGGGATTGATGAAGTTTCCGCAGCTCGGGGAGACAAGTTA; TGTCAAGATTCCATGATGAAACTCAAGGGCGTTGTTGCTGGCGCTCGTTCCAAAGGAGAA; CACAAACAGAAAATCTTTTTAACCATCTCCTTTGGAGGAATCAAAATCTTTGATGAGAAG; ACAGGGGCCCTTCAGCATCATCATGCTGTTCATGAAATATCCTACATTGCAAAGGACATT; ACAGATCACCGGGCCTTTGGATATGTTTGTGGGAAGGAAGGGAATCACAGATTTGTGGCC; ATAAAAACAGCCCAGGCGGCTGAACCTGTTATTCTGGACTTGAGAGATCTCTTTCAACTC; ATTTATGAATTGAAGCAAAGAGAAGAATTAGAAAAAAAGGCACAAAAGGATAAGCAGTGT; GAACAAGCTGTGTACCAGACAATATTGGAAGAGGATGTTGAAGATCCTGTGTACCAGTAC; ATTGTGTTTGAGGCTGGACACGAGCCAATCCGTGATCCCGAAACGGAAGAAAACATTTAT; CAGGTTCCCACCAGCCAAAAGAAGGAAGGTGTTTATGATGTGCCAAAAAGTCAACCTGTA; AGTGCTGTGACCCAATTAGAACTTTTTGGGGACATGTCCACACCCCCTGATATAACCTCT; CCCCCCACTCCTGCAACTCCAGGTGATGCCTTTATCCCATCTTCATCTCAGACCCTTCCA; GCGAGTGCAGATGTGTTTAGTTCTGTACCTTTCGGCACTGCTGCTGTACCCTCAGGTTAC; GTTGCAATGGGCGCTGTCCTCCCGTCCTTCTGGGGTCAGCAGCCCCTCGTCCAACAGCAG; ATGGTCATGGGTGCCCAGCCACCAGTCGCTCAGGTGATGCCGGGGGCTCAGCCCATCGCA; TGGGGCCAGCCGGGTCTCTTTCCTGCCACTCAGCAGCCCTGGCCAACTGTGGCCGGGCAG; TTTCCGCCAGCCGCCTTCATGCCCACACAAACTGTTATGCCTTTGCCAGCTGCCATGTTC; CAAGGTCCCCTCACCCCCCTTGCCACCGTCCCAGGCACGAGTGACTCCACCAGGTCAAGT; CCACAGACCGACAAGCCCAGGCAGAAAATGGGCAAAGAAACGTTTAAGGATTTCCAGATG; GCCCAGCCTCCGCCCGTGCCCTCCCGCAAACCCGACCAGCCCTCCCTCACCTGTACCTCA; GAGGCCTTCTCCAGTTACTTCAACAAAGTCGGGGTGGCACAGGATACAGACGACTGTGAT; GACTTTGACATCTCCCAGTTGAATTTGACCCCTGTGACTTCTACCACACCATCGACCAAC; TCACCTCCAACCCCAGCCCCTAGACAGAGCTCTCCATCCAAATCATCTGCATCCCATGCC; AGTGATCCTACCACAGATGACATCTTTGAAGAGGGCTTTGAAAGTCCCAGCAAAAGCGAA; GAGCAAGAAGCTCCTGATGGATCACAGGCCTCATCCAACAGTGATCCATTTGGTGAGCCC; AGTGGGGAGCCCAGTGGTGATAATATAAGTCCACAGGCCGGTAGCTAG; ; Clone variation with respect to NM_021080.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021080 unedited; CTGTGGTTCGGCTCATAAAGCAGGCACACAAGAGGGTGTCAACCGCCGAGAGAACCCAGA; GGCAGGGAGTCCGAGATGGGGGGAGGTCGTGTCGCGGCGTCTGAAAGGGGCCACTGGCAC; TCAAAAAGAGTGAATGAAATGTGCAGCTCAGAGTGTCATTTCTGAAGGGAGGAGTCTTTC; TCTTGGAGAAGAGTCCTCAATGAGCCTGGCCGAGGCCCGGGATCTGTGTGAAGTGGACTA; AGGATTAAGTAGGATGTCAACTGAGACAGAACTTCAAGTAGCTGTGAAAACCAGCGCCAA; GAAAGACTCCAGAAAGAAAGGTCAGGATCGCAGTGAAGCCACTTTGATAAAGAGGTTTAA; AGGTGAAGGGGTNCCGGTACAAAGCCAAATTGATCGGGATTGATGAAGTTTCCGCAGCTC; GGGGAGACAAGTTATGTCAAGATTCCATGATGAAACTCAAGGGGCGTTGNTTGCTGGCGC; CTCGTTCCAAAGGGAGAACACCAAACAGAAATCTTTNTAACCATCTNCTTTTGGAGGAAT; CAAAATCTTTGATGAGAAGACAGGGGGCCCTTCAGCATCATCATGCCTGGTCATGAAATA; TCCTACATTGCAAAGGACATTACAGATCACCGGGCCTGGAATTTTTNTTTGTGGAAAAGA; GGAAGGGATCCCAAATATTTGTGGCATAAAAACCAGCCCAGCGGGCTGACCCTGTATNCT; GACTTTGAAAAAACTCTTTCACTCATTTTTGAATTGAGCCAAGGGAAGATTANAAAAAAA; GCCCAAAGGTTANCCNTGGGGACAAACTGGGACCGCATATTGAA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021080 unedited; AAAGCTGAGAAAGTATTCATTTATTGTACTTATGTTTAGAGCTTCTTAAAAATATAGCTT; TTTATCTTTCTCATCATGGGATCTGATGTCTTTTCCTACTCACAGAATGAAGGTTCGTAC; TGAAAGCTGTCTTTCTTCACCAGGATGCAGAATAGCTAAAGGACTGTTTTGGCAACATTC; GTGATCATAATGAATAATCAACCACTTATTTGTCTTGTAATTTCAAGTTAATTCATTTCA; CTGAGGCTTTTTTTCTCCCCAGTTAGATTTCTTCACCCATATCTAAAAAAAGTCAAAAGC; AATACAAAAATTTGTACACCTATTAATTTTCAAACATGACAAAAAAAGGAAAGGGGGGAA; AATGGCAGACCAGGCCCCATGGAGTGACAAAAAACACATCATCCTATGTGAAAAGGCATA; TGGATGACGATATTGTGGTCACAGAAGACCCTTTGCTTTTGCTTAAAGAAGTCAGTTCCA; ACCCTGTTGTAATCCTCTGATGCCTGTCACTCCAAATTTGGTGTCTCAACAGTGGTCAAC; AGGTAGAGAAATAAAAAGGGAATTAATAATTTTGCACACTGAGTCATCTTATACCCAGCT; ATGAGGGCTCAAATATTTGTTGAGTAAGCATTTGCTTGATTTCTGATTTAATGTTGGGTG; GATCTTTCTATACTTTTTTTGTGTGCTGCCATAGATATCTGCCATTGGTTGCCAAAAATG; CTTAGTTCCCTCTTCTGAGCGAGTTCCATTGGGCAATCATGAATTTCTTGTGGGAAGAGG; TGAAAGTATACAAGAGAGCCTGTCGGGATGCTGATGTCCATGCCAGTCTTGAGCACCCAC; CACGAGCTCGCATCCGAGCCATTTCTTAGTCTGGTGATCTGCGCGTCAGAGGCTCGGGTT; CCAAACCTGC;
• Restriction Sites: NotI-NotI
• ACCN: NM_021080
• Insert Size: 3200 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_021080.3, NP_066566.3
• RefSeq Size: 2580 bp
• RefSeq ORF: 1668 bp
• Locus ID: 1600
• UniProt ID: O75553
• Cytogenetics: 1p32.2
• Domains: PID
• Summary: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]; Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1, 3, 4, 6, and 7 all encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.