SRPR beta (SRPRB) (NM_021203) Human Untagged Clone

SKU SC111909

SRPRB (untagged)-Human signal recognition particle receptor, B subunit (SRPRB)

Product Data

• Type: Human Untagged Clone
• Target Symbol: SRPR beta
• Synonyms: APMCF1; SR-beta
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111909 sequence for NM_021203 edited (data generated by NextGen Sequencing); ATGGCTTCCGCGGACTCGCGCCGGGTGGCAGATGGCGGCGGTGCCGGGGGCACCTTCCAG; CCCTACCTAGACACCTTGCGGCAGGAGCTGCAGCAGACGGACCCAACGCTGTTGTCAGTA; GTGGTGGCGGTTCTTGCGGTGCTGCTGACGCTAGTCTTCTGGAAGTTAATCCGGAGCAGA; AGGAGCAGTCAGAGAGCTGTTCTTCTTGTTGGCCTTTGTGATTCCGGGAAAACGTTGCTC; TTTGTCAGGTTGTTAACAGGCCTTTATAGAGACACTCAGACGTCCATTACTGACAGCTGT; GCTGTATACAGAGTCAACAATAACAGGGGCAATAGTCTGACCTTGATTGACCTTCCCGGC; CATGAGAGTTTGAGGCTTCAGTTCTTAGAGCGGTTTAAGTCTTCAGCCAGGGCTATTGTG; TTTGTTGTGGATAGTGCAGCATTCCAGCGAGAGGTGAAAGATGTGGCTGAGTTTCTGTAT; CAAGTCCTCATTGACAGTATGGGTCTGAAGAATACACCATCATTCTTAATAGCCTGCAAT; AAGCAAGATATTGCAATGGCAAAATCAGCAAAGTTAATTCAACAGCAGCTGGAGAAAGAA; CTCAACACCTTACGAGTTACCCGTTCTGCTGCCCCCAGCACACTGGACAGTTCCAGCACT; GCCCCTGCTCAGCTGGGGAAGAAAGGCAAAGAGTTTGAATTCTCACAGTTGCCCCTCAAA; GTGGAGTTCCTGGAGTGCAGTGCCAAGGGTGGAAGAGGGGACGTGGGCTCTGCTGACATC; CAGGACTTGGAGAAATGGCTGGCTAAAATTGCCTGA; ; Clone variation with respect to NM_021203.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021203 unedited; GGGGTTGGTATTTTGTAATACGACTCACTATAGGGGCGGCCGCGAATTCGCACGAGGCGC; GTCTCATCCATGGCTTCCGCGGACTCGCGCCGGGTGGCAGATGGCGGCGGTGCCGGGGGC; ACCTTCCAGCCCTACCTAGACACCTTGCGGCAGGAGCTGCAGCAGACGGACCCAACGCTG; TTGTCAGTAGTGGTGGCGGTTCTTGCGGTGCTGCTGACGCTAGTCTTCTGGAAGTTAATC; CGGAGCAGAAGGAGCAGTCAGAGAGCTGTTCTTCTTGTTGGCCTTTGTGATTCCGGGAAA; ACGTTGCTCTTTGTCAGGTTGTTAACAGGCCTTTATAGAGACACTCAGACGTCCATTACT; GACAGCTGTGCTGTATACAGAGTCAACAATAACAGGGGCAATAGTCTGACCTTGATTGAC; CTTCCCGGCCATGAGAGTTTGAGGCTTCAGTTCTTAGAGCGGTTTAAGTCTTCAGCCAGG; GCTATTGTGTTTGTTGTGGATAGTGCAGCATTCCAGCGAGAGGTGAAAGATGTGGCTGAG; TTTCTGTATCAAGTCCTCATTGACAGTATGGGTCTGAAGAATACACCATCATTCTTAATA; GCCTGCAATAAGCAAGATATTGCAATGGCAAAATCAGCAAAGTTAATTCAACAGCAGCTG; GAGAAAGAACTCAACACCTTACGAGTTACCCGTTCTGCTGCCCCCAGCACACTGGACAGT; TCCAGCACTGCCCCTGCTCNAGCTGGGAAGAAAGCANAGAGTTTGAATTCTCACAGGTGC; CCCTCAAAGTGGAGTTCCTGGAGTGCACTGCCAAGGGTGGAAAGAGGGACGNTGGCTCTG; CTGACATTCAGAACTTTGGAGAATGGCTTGCTAAAATTGCCTGAGAAGCAACTCTAAACC; ACAGACCTGTATGTGTGACCCACATTTTGGGAAAGGTCTGTGGG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021203 unedited; CGTTGTGGACCGCAGGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTCAAAAGGC; AACTTTTTTTTTTTTCTTGGCATCAATGAATATGCACTTCAAAAATCTACAGAGAACTTT; TTTCACTTTGTATTTGTTCCACAGCATTCTAGCCAGGAGTACAAAATAGGAGCTCTTCAA; GCAGCACATGAAGATGGCCCAGGAGCCTTCAGCCATCCAGAGCAGCAGAGCAGCACCTAA; ATCTCCACACACTTCCCAGTATAACCACTAAGAACACACTAGACCCTTGGCATTAGGGGA; TTTATCATTTCCAGTTCTATTATCTGGGAATGACTCCAAGGGTTTGTGACAAGCTTTTGA; AACGTAAGTGCTAAGACGAGTGTGGACAAGTCACTGAGCTAATGAAGAATAGACCCACTG; TCTGCTTGGCTCTGCTATTTTGTACCTGTCTTCACATGTGGGGAAACTTCATAACTGTGC; CCACAAATCAGAGAAATTCGCAAAGGACTAGACAATGTATTGCCTGTGAACTTCAGAGGC; AACTGGAAATAGTGCAACTGGAAATCAACTAGCTTCATACATAGGCGGATTTGTTTCCAG; GGACCAAAAGCACAGAAGATAAGAAAACTTTTCAGGTGATGGCCATATNCTCATCATATC; CTCTCTGTGGGAAGTCTGCCTGGTGTACANAAACCTTGACCTACATCAGTTACACCTAAC; AAGGGGAGATACGGCATCAGATAAAGTACTTGTTTGAAGGCAGCCATAAGGAGACTGAAC; TTAAAAAAAAAAAAAAATTCAGCTGTTTTAACATACTTGTTTCAGACAAAGAATGTTCTA; ACAATTTGTACCTTTCTAATAATCCAATACACAGACTTTTCAAACTGGGGTACAATCCAG; TTTGGGCTTAAACTGCTTAGGCATTTTC;
• Restriction Sites: NotI-NotI
• ACCN: NM_021203
• Insert Size: 1830 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_021203.2, NP_067026.2
• RefSeq Size: 1745 bp
• RefSeq ORF: 816 bp
• Locus ID: 58477
• UniProt ID: Q9Y5M8
• Cytogenetics: 3q22.1
• Protein Families: Druggable Genome, Transmembrane
• Summary: The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane. [provided by RefSeq, Jul 2008]