SEC23B (NM_006363) Human Untagged Clone

SKU SC110163

SEC23B (untagged)-Human Sec23 homolog B (S. cerevisiae) (SEC23B), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: SEC23B
• Synonyms: CDA-II; CDAII; CDAN2; CWS7; HEMPAS; hSec23B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006363, the custom clone sequence may differ by one or more nucleotides; ; ; ATGGCGACATACCTGGAGTTCATCCAGCAGAATGAAGAACGGGATGGTGTGCGTTTTAGTTGGAACGTGT; GGCCTTCCAGCCGGCTGGAGGCTACAAGAATGGTTGTACCCCTGGCTTGTCTCCTTACTCCTTTGAAAGA; ACGTCCAGACCTACCTCCTGTACAATATGAACCTGTGCTTTGCAGCAGGCCAACTTGTAAAGCTGTTCTC; AACCCACTTTGTCAGGTTGATTATCGAGCAAAACTTTGGGCCTGTAATTTCTGTTTTCAAAGAAATCAGT; TTCCTCCAGCTTATGGAGGCATATCTGAGGTGAATCAACCTGCCGAATTGATGCCCCAGTTTTCTACAAT; TGAGTACGTGATACAGCGAGGTGCTCAGTCCCCTCTGATCTTTCTCTATGTGGTTGACACATGCCTGGAG; GAAGATGACCTTCAAGCACTCAAAGAGTCCCTGCAGATGTCCCTGAGTCTTCTTCCTCCAGATGCTCTGG; TGGGTCTGATCACATTTGGAAGGATGGTGCAGGTTCATGAGCTAAGCTGTGAAGGAATCTCCAAAAGTTA; TGTCTTCCGAGGGACCAAGGATTTAACTGCAAAGCAAATACAGGATATGTTGGGCCTGACCAAGCCAGCC; ATGCCCATGCAGCAAGCACGACCTGCACAACCACAGGAGCACCCTTTTGCTTCAAGCAGATTTCTGCAGC; CTGTTCACAAGATTGATATGAACCTCACTGATCTTCTTGGGGAGCTACAGAGGGACCCATGGCCAGTAAC; TCAGGGGAAGAGACCTTTGCGATCCACTGGTGTGGCTTTGTCCATTGCTGTTGGCTTGCTGGAGGGCACT; TTTCCAAACACAGGAGCCAGGATCATGCTGTTTACTGGAGGTCCCCCTACCCAAGGGCCTGGCATGGTGG; TTGGAGATGAATTAAAGATTCCTATTCGTTCTTGGCATGATATTGAGAAAGATAATGCACGATTCATGAA; AAAGGCAACCAAGCACTATGAGATGCTTGCTAATCGAACAGCTGCAAATGGTCACTGCATTGATATTTAT; GCTTGTGCCCTTGATCAAACTGGACTTTTGGAGATGAAGTGTTGTGCAAATCTTACTGGAGGCTACATGG; TAATGGGAGATTCTTTCAACACTTCTCTCTTCAAGCAGACATTCCAAAGAATCTTTACTAAAGATTTTAA; TGGAGATTTCCGAATGGCATTTGGTGCTACTTTGGACGTAAAGACCTCTCGGGAACTGAAGATTGCAGGA; GCCATTGGTCCATGCGTATCTCTGAATGTGAAAGGACCGTGTGTGTCAGAAAATGAGCTTGGTGTTGGTG; GCACGAGTCAGTGGAAAATCTGTGGCCTAGATCCTACATCTACACTTGGCATCTATTTTGAAGTTGTCAA; TCAGCACAACACCCCGATCCCCCAAGGAGGCAGAGGAGCCATCCAGTTTGTCACGCATTATCAGCACTCC; AGCACCCAGAGACGCATCCGCGTGACCACCATCGCCCGAAATTGGGCAGATGTACAGAGTCAGCTCAGGC; ACATAGAAGCAGCATTTGACCAGGAGGCTGCGGCAGTGTTGATGGCACGGCTTGGGGTGTTCCGAGCGGA; GTCAGAGGAGGGGCCCGATGTGCTCCGGTGGCTGGACCGACAACTCATCCGACTGTGTCAAAAGTTTGGA; CAGTATAACAAAGAAGACCCCACTTCTTTTAGGTTATCAGATTCCTTTTCTCTATATCCTCAGTTTATGT; TCCATCTGAGAAGATCTCCATTTCTTCAAGTGTTTAACAACAGTCCTGATGAGTCGTCATATTACAGACA; TCATTTTGCCCGGCAGGACCTGACCCAGTCCCTCATCATGATCCAGCCCATTCTCTACTCTTACTCCTTT; CATGGGCCACCAGAGCCAGTACTCTTGGATAGCAGCAGCATTCTAGCTGACAGAATTTTGCTGATGGATA; CTTTCTTTCAAATTGTCATTTATCTTGGTGAGACCATAGCCCAGTGGCGTAAAGCTGGCTACCAGGACAT; GCCCGAGTATGAAAACTTCAAGCACCTTCTGCAGGCACCACTGGATGATGCTCAAGAAATTCTGCAAGCA; CGCTTCCCGATGCCACGTTACATCAACACGGAGCATGGAGGCAGTCAGGCTCGATTCCTTTTGTCCAAAG; TGAACCCATCTCAGACACACAATAACCTGTATGCTTGGGGACAGGAAACTGGAGCACCCATCCTAACTGA; TGATGTTAGCCTGCAGGTGTTCATGGACCATTTGAAGAAGCTGGCTGTCTCCAGTGCCTGTTAA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006363 unedited; TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTCTAGCTAGTTCC; CTTTTAGACTATGGCGACATACCTGGAGTTCATCCAGCAGAATGAAGAACGGGATGGTGT; GCGTTTTAGTTGGAACGTGTGGCCTTCCAGCCGGCTGGAGGCTACAAGAATGGTTGTACC; CCTGGCTTGTCTCCTTACTCCTTTGAAAGAACGTCCAGACCTACCTCCTGTACAATATGA; ACCTGTGCTTTGCAGCAGGCCAACTTGTAAAGCTGTTCTCAACCCACTTTGTCAGGTTGA; TTATCGAGCAAAACTTTGGGCCTGTAATTTCTGTTTTCAAAGAAATCAGTTTCCTCCAGC; TTATGGAGGCATATCTGAGGTGAATCAACCTGCCGAATTGATGCCCCAGTTTTCTACAAT; TGAGTACGTGATACAGCGAGGTGCTCAGTCCCCTCTGATCTTTCTCTATGTGGTTGACAC; ATGCCTGGAGGAAGATGACCTTCAAGCACTCAAAGAGTCCCTGCAGATGTCCCTGAGTCT; TCTTCCTCCAGATGCTCTGGTGGGTCTGATCACATTTGGAAGGATGGTGCAGGTTCATGA; GCTAAGCTGTGAAGGAATCTCCAAAAGTTATGTCTTCCGAGGGACCAAGGATTTAACTGC; AAAGCAAATCAGGATATGTTGGGCCTGACCAAGCCAGCCATGCCCATGCAGCAAGCACGA; CCTGCACAACACAGGAGCACCCTTTTGCTTAAGCAGATTTCTGCAGCCTGTTCACAGAAT; GATATGAACCTCACTGATCTTCTTTGGGAGCTCAGAGGNACCCATGCCAGTACTCANGGG; AAGAACCCTTGCATCACTGGNGNNNGCTTGTCATTGCTGTGGCTGGCTC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006363 unedited; GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTCAGGAAAACACATTTGTATTAGC; AATATTTTAGCCAGTACTTTCTGCATCTAGATTTATTTCCTTTATGATCATTAAGATTCT; CACCTAAACAAGCTGCCAAAATACATTACCTCTGATTTTATTTAGATTCTAAAAGTTAGG; ATACAAAAAGCACATAAACATCTACAAGTACCAAAACATTTATGACCTTATAATTTTATA; GTGCAAGAAAAAGGACAAAGACAGGAATACAAATAAATTATAATCTAAAGAGTTACATAT; AAAATGTCCTTGATTATTTGTTAAAATCTGCTAGAAAAGTAACAGGAATGTTATCAAGCC; TTTCTAGACATTTTGAACACAATCTGACACCGTTGCATTTCCTGGTTGTATCCTCAGCTT; AACAGGCACTGGAGACAGCCAGCTTCTTCAAATGGTCCATGAACACCTGCAGGCTAACAT; CATCAGTTAGGATGGGTGCTCCAGTTTCCTGTCCCCAAGCATACAGGTTATTGTGTGTCT; GAGATGGGTTCACTTTGGACAAAAGGAATCGAGCCTGACTGCCTCCATGCTCCGTGTTGA; TGTAACGTGGCATCGGGAAGCGTGCTTGCAGAATTTCTTGAGCATCATCCAGTGGTGCCT; GCAGAAGGTGCTTGAAGTTTCCATACTCGGCATGTCCTGGTAGCCAGCTTTACGCCACTG; GGCTATGGTCTCACCAGGATAAATGACAATTTGAAAGAAGTATCCATCAGCAAAATTCTG; TCAGCTAGAATGCTGCTGCTAATCAAGATACTGGCTCTGTTGGCCACTGAAGGAGTAAGT; AAGAATGGCTGAACATGAGAGGAACTGGCCACGTCTGCCGGCAAATGATGTCTGTAAATG; ACACTCATCAGGCTGTGGTTAACCTTGAGAAAGGAAAATTTTCAATGGACAAACCGAGGA; ATGAG;
• Restriction Sites: NotI-NotI
• ACCN: NM_006363
• Insert Size: 2820 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006363.4, NP_006354.2
• RefSeq Size: 3429 bp
• RefSeq ORF: 2304 bp
• Locus ID: 10483
• UniProt ID: Q15437
• Cytogenetics: 20p11.23
• Domains: Gelsolin, Sec23_helical, Sec23_trunk, zf-Sec23_Sec24
• Summary: The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]; Transcript Variant: This variant (1) uses an alternative splice site and lacks a segment in the 5' UTR, as compared to variant 2. Variants 1, 2, 3 and 4 encode the same isoform (1).