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GTF2IRD1 (NM_005685) Human Untagged Clone

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SKU
SC110071
GTF2IRD1 (untagged)-Human GTF2I repeat domain containing 1 (GTF2IRD1), transcript variant 2
  $865.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol GTF2IRD1
Synonyms BEN; CREAM1; GTF3; hMusTRD1alpha1; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC110071 sequence for NM_005685 edited (data generated by NextGen Sequencing)
ATGGCCTTGCTGGGTAAGCGCTGTGACGTCCCCACCAACGGCTGCGGACCCGACCGCTGG
AACTCCGCGTTCACCCGCAAAGACGAGATCATCACCAGCCTCGTGTCTGCCTTAGACTCC
ATGTGCTCAGCGCTGTCCAAACTGAACGCCGAGGTGGCCTGTGTCGCCGTGCACGATGAG
AGCGCCTTTGTGGTGGGCACAGAGAAGGGGAGAATGTTCCTGAATGCCCGGAAGGAGCTA
CAGTCAGACTTCCTCAGGTTCTGCCGAGGGCCCCCGTGGAAGGATCCGGAGGCAGAGCAC
CCCAAGAAGGTGCAGCGGGGCGAGGGTGGAGGCCGTAGCCTCCCTCGGTCCTCCCTGGAA
CATGGCTCAGATGTGTACCTTCTGCGGAAGATGGTAGAGGAGGTGTTTGATGTTCTTTAT
AGCGAGGCCCTGGGAAGGGCCAGTGTGGTGCCACTGCCCTATGAGAGGCTGCTCAGGGAG
CCAGGGCTGCTGGCCGTGCAGGGGCTGCCCGAAGGCCTGGCCTTCCGAAGGCCAGCCGAG
TATGACCCCAAGGCCCTCATGGCCATCCTGGAACACAGCCACCGCATCCGCTTCAAGCTC
AAGAGGCCACTTGAGGATGGCGGGCGGGACTCGAAGGCCCTGGTGGAGCTGAACGGTGTC
TCCCTGATTCCCAAGGGGTCACGGGACTGTGGCCTGCATGGCCAGGCCCCCAAGGTGCCA
CCCCAGGACCTGCCCCCAACCGCCACCTCCTCCTCCATGGCCAGCTTCCTGTACAGCACG
GCGCTCCCCAACCACGCCATTCGAGAGCTCAAGCAGGAAGCACCTTCCTGCCCCCTTGCC
CCCAGCGACCTGGGCCTGAGTCGGCCCATGCCAGAGCCCAAGGCCACCGGTGCCCAAGAC
TTCTCCGACTGTTGTGGACAGAAGCCCACTGGGCCTGGTGGGCCTCTCATCCAGAACGTC
CATGCCTCCAAGCGCATTCTCTTCTCCATCGTCCATGACAAGTCAGAGAAGTGGGACGCC
TTCATAAAGGAAACCGAGGACATCAACACGCTCCGGGAGTGTGTGCAGATCCTGTTTAAC
AGCAGATATGCGGAAGCCCTGGGCCTGGACCACATGGTCCCCGTGCCCTACCGGAAGATT
GCCTGTGACCCGGAGGCTGTGGAGATCGTGGGCATCCCGGACAAGATCCCCTTCAAGCGC
CCCTGCACTTATGGAGTCCCCAAGCTGAAGCGGATCCTGGAGGAGCGCCATAGTATCCAC
TTCATCATTAAGAGGATGTTTGATGAGCGAATTTTCACAGGGAACAAGTTTACCAAAGAC
ACCACGAAGCTGGAGCCAGCCAGCCCGCCAGAGGACACCTCTGCAGAGGTCTCTAGGGCC
ACCGTCCTTGACCTTGCTGGGAATGCTCGGTCAGACAAGGGCAGCATGTCTGAAGACTGT
GGGCCAGGAACCTCCGGGGAGCTGGGCGGGCTGAGGCCGATCAAAATTGAGCCAGAGGAT
CTGGACATCATTCAGGTCACCGTCCCAGACCCCTCGCCAACCTCTGAGGAAATGACAGAC
TCGATGCCTGGGCACCTGCCATCGGAGGATTCTGGTTATGGGATGGAGATGCTGACAGAC
AAAGGTCTGAGTGAGGACGCGCGGCCCGAGGAGAGGCCCGTGGAGGACAGCCACGGTGAC
GTGATCCGGCCCCTGCGGAAGCAGGTGGAGCTGCTCTTCAACACACGATACGCCAAGGCC
ATTGGCATCTCGGAGCCCGTCAAGGTGCCGTACTCCAAGTTTCTGATGCACCCGGAGGAG
CTGTTTGTGGTGGGACTGCCTGAAGGCATCTCCCTCCGCAGGCCCAACTGCTTCGGGATC
GCCAAGCTCCGGAAGATTCTGGAGGCCAGCAACAGCATCCAGTTTGTCATCAAGAGGCCC
GAGCTGCTCACTGAGGGAGTCAAAGAGCCCATCATGGATAGTCAAGAGAGGGATTCCGGG
GACCCTCTGGTGGACGAGAGCCTGAAGAGACAGGGCTTTCAAGAAAATTATGACGCGAGG
CTCTCACGGATCGACATCGCCAACACACTAAGGGAGCAGGTCCAGGACCTTTTCAATAAG
AAATACGGGGAAGCCTTGGGCATCAAGTACCCGGTCCAGGTCCCCTACAAGCGGATCAAG
AGTAACCCCGGCTCCGTGATCATCGAGGGGCTGCCCCCAGGAATCCCGTTCCGAAAGCCC
TGTACCTTCGGCTCCCAGAACCTGGAGAGGATTCTTGCTGTGGCTGACAAGATCAAGTTC
ACAGTCACCAGGCCTTTCCAAGGACTCATCCCAAAGCCTGATGAAGATGACGCCAACAGA
CTCGGGGAGAAGGTGATCCTGCGGGAGCAGGTGAAGGAACTCTTCAACGAGAAATACGGT
GAGGCCCTGGGCCTGAACCGGCCGGTGCTGGTCCCTTATAAACTAATCCGGGACAGCCCA
GACGCCGTGGAGGTCACGGGTCTGCCTGATGACATCCCCTTCCGGAACCCCAACACGTAC
GACATCCACCGGCTGGAGAAGATCCTGAAGGCCCGAGAGCATGTCCGCATGGTCATCATT
AACCAGCTCCAACCCTTTGCAGAAATCTGCAATGATGCCAAGGTGCCAGCCAAAGACAGC
AGCATTCCCAAGCGCAAGAGAAAGCGGGTCTCGGAAGGAAATTCCGTCTCCTCTTCCTCC
TCGTCTTCCTCTTCCTCGTCCTCTAACCCGGATTCAGTGGCATCGGCCAACCAGATCTCA
CTCGTGCAATGGCCAATGTACATGGTGGACTATGCCGGCCTGAACGTGCAGCTCCCGGGA
CCTCTTAATTACTAG

Clone variation with respect to NM_005685.3
801 c=>t
5' Read Nucleotide Sequence
>OriGene 5' read for NM_005685 unedited
GGTACANNATTTATGTATACGACTTACTTATAGGGCGGNCGCAGAATCGGNACGAGGCGG
NAGGAGGCTGAGTCCTGGCCGCGGGCCGGGGCCGGGGCGCCGCTGGCAGGAGCGCTTGGG
GATCCTCCAAGGCGACCATGGCCTTGCTGGGTAAGCGCTGTGACGTCCCCACCAACGGCT
GCGGACCCGACCGCTGGAACTCCGCGTTCACCCGCAAAGACGAGATCATCACCAGCCTCG
TGTCTGCCTTAGACTCCATGTGCTCAGCGCTGTCCAAACTGAACGCCGAGGTGGCCTGTG
TCGCCGTGCACGATGAGAGCGCCTTTGTGGTGGGCACAGAGAAGGGGAGAATGTTCCTGA
ATGCCCGGAAGGAGCTACAGTCAGACTTCCTCAGGTTCTGCCGAGGGCCCCCGTGGAAGG
ATCCGGAGGCAGAGCACCCCAAGAAGGTGCAGCGGGGCGAGGGTGGAGGCCGTAGCCTCC
CTCGGTCCTCCCTGGAACATGGCTCAGATGTGTACCTTCTGCGGAAGATGGCAGAGGAGG
TGTTTGATGTCTTTCTATAGCGAGGCCCTGGGAAAGGCCAGTGTGGTGCCCACTGCCCTA
TGAAAGGCTGCTCAGGGAGCCCAGCGCTGTTGGCCGTGCAGGGGCCTGCCCGAAAGCCCT
GGCCTCTTCGAACGCCACCCCGAGTATGACCCCAAGGGCCTCATGGCCCTCCTGGAACAC
ACCCCCCCGATCCCGCTCAAGCTCCAGAAGCCACTTGAGGATCGCGGCCGGACTTCCAAG
GCCTGGTGGAGCTGAACGTTGCCTCCCTGATCCCAAGGGTCCAGGGACTGTGGCCTGCTT
GCCAGGCCTCCCAAGGGCCCCCCCAGACCTGCCCCACCGCCACTTCTTCTCCAGGGCCCC
TTCCTGTCCACCCGGCCCTCCCAACCCCCCTTCAGACCCCACCCGAAC
3' Read Nucleotide Sequence
>OriGene 3' read for NM_005685 unedited
CAATCTAGTGTCGAGTTTTTTTTTTTTTTTTTTACTTATTTAAAAAGGCCTTGGTGGCAG
GAATATAGTGTAAAAATCATTGGAAAAACTAAAAGGCATCGATACATATCCGAATATACA
TTTTGTACATAAATTACATTTCCTTTAGTCTTTCTGAGTGAGGTCCTGATTCAGTACTGA
GGTCTAGTAATTAAGAGGTCCCGGGAGCTGCACGTTCAGGCCGGCATAGTCCACCATGTA
CATTGGCCATTGCACGAGTGAGATCTGGTTGGCCGATGCCACTGAATCCGGGTTAGAGGA
CGAGGAAGAGGAAGACGAGGAGGAAGAGGAGACGGAATTTCCTTCCGAGACCCGCTTTCT
CTTGCGCTTGGGAATGCTGCTGTCTTTGGCTGGCACCTTGGCATCATTGCAGATTTCTGC
AAAGGGTTGGAGCTGGTTAATGATGACCATGCGGACATGCTCTCGGGCCTTCAGGATCTT
CTCCAGCCGGTGGATGTCGTACGTGTTGGGGTTCCGGAAGGGGATGTCATCATGCAGACC
CGTGACCTCCACGGCGTCTGGGCTGTCCCGGATTAGTTTATAAGGGACCAGCACCGGCCG
GTTCATGCCCAGGGCCTCACCGTATTTCTCGNTGAAGAGTTCCCTCACCTGCTCCCGCAG
GATCACCTTTCTTCCCGAGTCTGTTGGCGTCATCCTCATCAAGGCTTTGAGATGAGTCCT
TGGAAAAGCCTGGAGACTGTGAACTTGATCATGTCAGCCCCAGCAAGAATCCTCTCCAGG
TTCTGGGACCCGAAGGTCAAGGCTTTCGGAACGGGATTCCTGGGGGCAGCCCCTCGATAT
TACGAAGCCGGGTTACTCTTGATTCCCTTGTAGGGACCTGTACAGTTCCTTGTTGCCAAG
CTTCCCGTATCTCTATGAAAGCCCCTGACTGCCCCTTATGGGTGGGAAGCGATCCGAGAA
CCCCGGCATATTTTTGAAACCGGCTTTTAGTCTTGCACAG
Restriction Sites NotI-NotI |
ACCN NM_005685
Insert Size 3000 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_005685.2, NP_005676.2
RefSeq Size 3078 bp
RefSeq ORF 2835 bp
Locus ID 9569
UniProt ID Q9UHL9
Cytogenetics 7q11.23
Domains GTF2I
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Basal transcription factors
Summary The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. provided by RefSeq, Nov 2010
Transcript Variant: This variant (2) uses an alternate splice site in the coding region, compared to variant 3. The encoded isoform (2) is shorter compared to isoform 3.
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Documents
Resources
"NM_005685" in other vectors (4)
SKU Description Size Price
RC218834 GTF2IRD1 (Myc-DDK-tagged)-Human GTF2I repeat domain containing 1 (GTF2IRD1), transcript variant 2 10 ug
$864.00
RC218834L3 Lenti ORF clone of Human GTF2I repeat domain containing 1 (GTF2IRD1), transcript variant 2, Myc-DDK-tagged 10 ug
$1,164.00
RC218834L4 Lenti ORF clone of Human GTF2I repeat domain containing 1 (GTF2IRD1), transcript variant 2, mGFP tagged 10 ug
$1,164.00
RG218834 GTF2IRD1 (tGFP-tagged) - Human GTF2I repeat domain containing 1 (GTF2IRD1), transcript variant 2 10 ug
$1,064.00

file-alt Citations

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