FGF13 (NM_004114) Human Untagged Clone

SKU SC109226

FGF13 (untagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: FGF13
• Synonyms: DEE90; FGF-13; FGF2; FHF-2; FHF2; LINC00889
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_004114 edited; ATGGCGGCGGCTATCGCCAGCTCGCTCATCCGTCAGAAGAGGCAAGCCCGCGAGCGCGAG; AAATCCAACGCCTGCAAGTGTGTCAGCAGCCCCAGCAAAGGCAAGACCAGCTGCGACAAA; AACAAGTTAAATGTCTTTTCCCGGGTCAAACTCTTCGGCTCCAAGAAGAGGCGCAGAAGA; AGACCAGAGCCTCAGCTTAAGGGTATAGTTACCAAGCTATACAGCCGACAAGGCTACCAC; TTGCAGCTGCAGGCGGATGGAACCATTGATGGCACCAAAGATGAGGACAGCACTTACACT; CTGTTTAACCTCATCCCTGTGGGTCTGCGAGTGGTGGCTATCCAAGGAGTTCAAACCAAG; CTGTACTTGGCAATGAACAGTGAGGGATACTTGTACACCTCGGAACTTTTCACACCTGAG; TGCAAATTCAAAGAATCAGTGTTTGAAAATTATTATGTGACATATTCATCAATGATATAC; CGTCAGCAGCAGTCAGGCCGAGGGTGGTATCTGGGTCTGAACAAAGAAGGAGAGATCATG; AAAGGCAACCATGTGAAGAAGAACAAGCCTGCAGCTCATTTTCTGCCTAAACCACTGAAA; GTGGCCATGTACAAGGAGCCATCACTGCACGATCTCACGGAGTTCTCCCGATCTGGAAGC; GGGACCCCAACCAAGAGCAGAAGTGTCTCTGGCGTGCTGAACGGAGGCAAATCCATGAGC; CACAATGAATCAACGTAG;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004114 unedited; GACTATTTTGTATACGACTCACTCATAGGGCGGCCGCGAATTCGCACGAGAAGAGTTGCA; AGGACTAGTCGAAGACTCGGAGGGGCCAGGGCGAGGGCGCGCTCCCCCGCGCGCTGCCTC; CTCCCTCCTCCCTCCGGCCGCCCGAGCTCCCGGCCTCTCTCCCGCCCGCGCTCACTCCCT; CCGCCCGCCTCCCTCCTCTGGCCCCCTCCGCGCGGCACAGGGCGGGGGGTGCCGCGAAAC; TCCGACCCGAGCCACTTGGACTTGCACAGTGTCCGCCGGGCGCAGGGGCCGACCGCACGC; AGTCGCGCAGTTCTGCCTCCGCCTGCCAGTCTCGCCCGCGATCCCGGCCCGGGGCTGTGG; CGTCGACTCCGACCCAGGCAGCCAGCAGCCCGCGCGGGAGCCGGACCGCCGCCGGAGGAG; CTCGGACGGCATGCTGAGCCCCCTCCTTGGCTGAAGCCCGAGTGCGGAGAAGCCCGGGCA; AACGCAGGCTAAGGAGACCAAAGCGGCGAAGTCGCGAGACAGCGGACAAGCAGCGGAGGA; GAAGGAGGAGGAGGCGAACCCAGAGAGGGGCAGCAAAAGAAGCGGTGGTGGTGGGCGTCG; TGGCCATGGCGGCGGCTATCGCCAGCTCGCTCATCCGTCAGAAGAAGGCAGCCCCGCGAG; CGCGAGAAATCCAACGCCTGCAAGTGTGTCAGCAGCCCCAGCCTAGGCAAGACCAGCTGC; GACAAAAACCAGTAAAAGCCTTTTCCCGGTCAAACTCTNCGGCTTCCAGAAGAGCGCAGA; AGAAGACCAGACCTCAGCTNAAGGTTATAGTACCAAGCTTACAGCCGACAAGCTACCACT; GCAGCTGCAGGCGGATGAACCATTGATGGCCCCCAAGAGAGGACGCACTTACCTCTGTTA; ACCCCTCCCTGTGGGCCGGAGGGTGGGCATCC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004114 unedited; GCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAATGAATATAAAGAGTTTA; TTCGGTGCGTATTTGGGTATACAACAACAAATATTAAACAACTTTTTTAAACTTTTTGTG; CACAGGACAGAAAACTGCCTGTACATGCTATGTCCACTTTTGGAACACAGATTTTTAACA; ATTATGAATGCACAAAATCTTACATATCATGCAACTCTATGCCAAGAACCCAACTTTCTT; CCATGCAACAGATATGAAGATCTAAATGGAAACCTAGCTAAGTCTTAAACACTTTTCCAG; TAGCAAGTATAATATATGTTGTTGAGGGAAAACCAGTCTTAACAATTCCTTGTACACAAT; ATTCATGTGCCAAATACAATGACAGGAAGACTCATACATATACAGATAAGACATTTCTTA; TTTTAACAACACAAAAGACAACATCACAGTTCCACAGTTCCTGTCTTTACACAAGAAGCC; ACAACAATAGTTTAACATGATACACAAATGGAATTAAGAGAAATCTACACTTGAGGATAA; TTTTTTGAAGTTCTCTTTACTGACTGGGGTTGACAATACAACTCAATTTCTACGCACAAA; GTACAGCACAATAACTTGACCAGAATACCACANATCTAAAAAAAAAAAAAAGAAAGAAAN; ACATTTGGTCAAACCACAAGAACGCTGTTACCTTGAGCCTGAGAAGCCAATTCAGATTCA; ACCCTGAATTTGGTTGATTNGGATTAAGTGACGCAAAAAGCCATATGAACATTGAATTCC; AGAAATCATAAGTTGACTATGCCCAAGGAAAGATACATGTGAATCAAGCCGAGATAGAAA; CATCAGCCAAGAAAACAACCCATTNACATAATTTTGTTTGCCCCGACAACAATTAGCAGN; AANTTTGGTTNGGTTGGNTTGGNTGGGTTTGAAAACAAATGGGGCTTTCAACTTNCTGGN; GGANAGAGCAANTTGATCACTTAAGCCTTGGAAACTTGTGATATTACCCAAGTTATGTGA; ATACTGGAAATG;
• Restriction Sites: NotI-NotI
• ACCN: NM_004114
• Insert Size: 2600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004114.2, NP_004105.1
• RefSeq Size: 2673 bp
• RefSeq ORF: 738 bp
• Locus ID: 2258
• UniProt ID: Q92913
• Cytogenetics: Xq26.3-q27.1
• Domains: FGF
• Protein Families: Secreted Protein
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton
• Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked cognitive disability mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]; Transcript Variant: This variant (1) represents the most predominant transcript and encodes isoform 1.