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COMMD5 (NM_014066) Human Untagged Clone

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SKU
SC108830
COMMD5 (untagged)-Human COMM domain containing 5 (COMMD5), transcript variant 1
  $300.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol COMMD5
Synonyms HCARG; HT002
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC108830 sequence for NM_014066 edited (data generated by NextGen Sequencing)
ATGTCTGCTGTGGGGGCTGCAACTCCATACCTGCATCATCCTGGTGATAGTCACAGTGGC
CGAGTGAGTTTCTTGGGGGCCCAGCTTCCTCCAGAGGTGGCAGCAATGGCCCGGCTACTA
GGGGACCTAGACAGGAGCACGTTCAGAAAGTTGCTGAAGTTTGTGGTCAGCAGCCTGCAG
GGGGAGGACTGCCGAGAGGCTGTGCAGCGTCTTGGGGTCAGCGCCAACCTGCCGGAGGAG
CAGCTGGGTGCCCTGCTGGCAGGCATGCACACACTGCTCCAGCAGGCCCTCCGTCTGCCC
CCCACCAGCCTGAAGCCTGACACCTTCAGGGACCAGCTCCAGGAGCTCTGCATCCCCCAA
GACCTGGTCGGGGACTTGGCCAGCGTGGTATTTGGGAGCCAGCGGCCCCTCCTTGATTCT
GTGGCCCAGCAGCAGGGGGCCTGGCTGCCGCATGTTGCTGACTTTCGGTGGCGGGTGGAT
GTAGCAATCTCCACCAGTGCCCTGGCTCGCTCCCTGCAGCCGAGCGTCCTGATGCAGCTG
AAGCTTTCAGATGGGTCAGCATACCGCTTTGAGGTCCCCACAGCCAAGTTCCAGGAGCTG
CGGTACAGCGTGGCCCTGGTCCTAAAGGAGATGGCAGATCTGGAGAAGAGGTGTGAGCGC
AGACTGCAGGACTGA

Clone variation with respect to NM_014066.3
5' Read Nucleotide Sequence
>OriGene 5' read for NM_014066 unedited
GAGGCGGGGACCAGGCCCGCTTTTGGCTGCATCAGCCGGGGATTGCCGGCGCCAGGTGCT
GGGGGCGACTCGGACAGCGGGAGCGTGGGGTGGAGTAGGATGGAGTCTCCCTTCCCGAGC
TGGGGGTGTGGGCCTAGGAAAGGCTGCTTCGCCGCTGTGTTCGGAGAGCTCTGGATACTG
CGGGGCTTTTCCGCGGAGGAGCGCCCGCCGGCATCTGCATCTGGGACCGACCTCCTGGGC
TGGCTGAATCAAAAGAGGAAGCAGCAGCAATGTCTGCTGTGGGGGCTGCAACTCCATACC
TGCATCATCCTGGTGATAGTCACAGTGGCCGAGTGAGTTTCTTGGGGGCCCAGCTTCCTC
CAGAGGTGGCAGCAATGGCCCGGCTACTAGGGGAACTAGACAGGAGCACGTTCAGAAAGT
TGCTGAAGTTTGTGGTCAGCAGCCTGCAGGGGGAGGAATGCCGAGAGGCTGTGCAGCGTC
TTGGGGTCAGCGCCAACCTGCCGGAGGAACAGCTGGGTGCCCTGCTGGCAGGCATGCACA
CACTGCTCCAG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_014066 unedited
TCTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGTTTTTAGC
TGCTTTACTTCCAAAAAGAAAAAAAGCATAGCTCTCTTTTTCAATTAAACAGAAAACTAC
ATAATTACGTTCAAACACTCACTGAAGAGCCTGCCTCATGGGAAGGGCAGGGCTGTCGTG
GGAAGAGTCAGCTGCACTTTGGCACCATCTCAGGGTGCCTTGGTCCAAGCCGGATCTGAA
TGGGACTGGTCAAGTGAGGGGTCAGTCCTGCAGTCTGCGCTCACACCTCTTCTCCAGATC
TGCCATCTCCTTTAGGACCAGGGCCACGCTGTACCGCAGCTCCTGGAACTTGGCTGTGGG
GACCTCAAAGCGGTATGCTGACCCATCTGAAAGCTTCAGCTGCATCAGGACGCTCGGCTG
CANGGAGCGAGCCANGGCACTGGTGGAGATTGCTACATCCACCCGCCACCGAAAGTCAGC
AACATGCGGCAGCCAGGCCCCCTGCTGCTGGGCCACAGAATCAAGGAGGGGCCGCTGGCT
CCCAATACCACGCTGGCCAAGTCCCCGACCAGGTCTTGGGGGATGCAGAGCTCCTGGAGC
TGGTCCCTGANAGTGTCAGGCTTCAGGCTGGTGGGGGGCANACGGAGGGCCTGCTGGAGC
ANTGTGTGCATGCCTGCCANCAGGGCACCCAGCTGCTCCTCCGGCAGGTTGGCGCTGACC
CCAGACGCTGACAGCCTCTCGGAGTTCTTCCCCTGGAAGCTGTTGACCACAACTTTACAA
CTTTTTGAACGGCTCCTGCTAGGCCCCTATAACCGGCCATTGCTGCCCCTTTGGAGAACT
GGGCCCCAGAAACCCTTGGGCCTGGGACTATACAGATAAGCCGTTGGAATTAACCCCCAA
CAGAATGGTGTTGTTNCTTTTGTAAGCACCCAGAGGTGTCCAAATCAAGCCGGGGGCCTC
CTCCGGAAACCCCAAT
Restriction Sites NotI-NotI |
ACCN NM_014066
Insert Size 1200 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_014066.2, NP_054785.2
RefSeq Size 3112 bp
RefSeq ORF 675 bp
Locus ID 28991
UniProt ID Q9GZQ3
Cytogenetics 8q24.3
Protein Families Druggable Genome
Summary May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966).UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 4. Variants 1 through 4 encode the same protein.
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Documents
Resources
"NM_014066" in other vectors (4)
SKU Description Size Price
RC209381 COMMD5 (Myc-DDK-tagged)-Human COMM domain containing 5 (COMMD5), transcript variant 1 10 ug
$450.00
RC209381L3 Lenti ORF clone of Human COMM domain containing 5 (COMMD5), transcript variant 1, Myc-DDK-tagged 10 ug
$750.00
RC209381L4 Lenti ORF clone of Human COMM domain containing 5 (COMMD5), transcript variant 1, mGFP tagged 10 ug
$750.00
RG209381 COMMD5 (tGFP-tagged) - Human COMM domain containing 5 (COMMD5), transcript variant 1 10 ug
$650.00

file-alt Citations

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