FANCI (NM_001113378) Human Tagged Lenti ORF Clone
- LentiORF®
SKU
RC226384L4
Lenti-ORF clone of FANCI (mGFP-tagged)-Human Fanconi anemia, complementation group I (FANCI), transcript variant 1
$2,034.00
3 Weeks*
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
|---|---|
| Target Symbol | FANCI |
| Synonyms | KIAA1794 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_001113378 |
| ORF Size | 3984 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001113378.1 |
| RefSeq ORF | 3987 bp |
| Locus ID | 55215 |
| UniProt ID | Q9NVI1 |
| Cytogenetics | 15q26.1 |
| MW | 149.1 kDa |
| Summary | The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001113378" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC226384 | FANCI (Myc-DDK-tagged)-Human Fanconi anemia, complementation group I (FANCI), transcript variant 1 | 10 ug |
$1,734.00
|
|
| RC226384L1 | Lenti-ORF clone of FANCI (Myc-DDK-tagged)-Human Fanconi anemia, complementation group I (FANCI), transcript variant 1 | 10 ug |
$2,034.00
|
|
| RC226384L2 | Lenti-ORF clone of FANCI (mGFP-tagged)-Human Fanconi anemia, complementation group I (FANCI), transcript variant 1 | 10 ug |
$2,034.00
|
|
| RC226384L3 | Lenti-ORF clone of FANCI (Myc-DDK-tagged)-Human Fanconi anemia, complementation group I (FANCI), transcript variant 1 | 10 ug |
$2,034.00
|
|
| RG226384 | FANCI (tGFP-tagged) - Human Fanconi anemia, complementation group I (FANCI), transcript variant 1 | 10 ug |
$1,934.00
|
|
| SC319029 | FANCI (untagged)-Human Fanconi anemia, complementation group I (FANCI), transcript variant 1 | 10 ug |
$1,735.00
|
|
Citations
CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI
Hu, Krieger, Lagundžin et al
Cell Death Discov (2019) 5, 105 DOI: 10.1038/s41420-019-0185-3
Hu, Krieger, Lagundžin et al
Cell Death Discov (2019) 5, 105 DOI: 10.1038/s41420-019-0185-3
AI Summary: OriGene products contributed to this study by providing the full-length FANCI transcript variant 1 C-terminal fusion with monomeric GFP (mGFP) construct in pLenti-C-mGFP-P2A-Puro and the full-length CTDP1 transcript variant 1 C-terminal fusion with myc and DDK epitopes in pCMV6-Entry, which were used to investigate the molecular interactions and functions of CTDP1 and FANCI in breast cancer DNA repair mechanisms.
Snippet: … Full-length FANCI transcript variant 1 C-terminal fusion with monomeric GFP (mGFP) construct in pLenti-C-mGFP-P2A-Puro was purchased from Origene. …Full-length FANCI transcript variant 1 C-terminal fusion with monomeric GFP (mGFP) construct in pLenti-C-mGFP-P2A-Puro was purchased from Origene. …
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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