Plg (NM_008877) Mouse Tagged ORF Clone
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
|---|---|
| Target Symbol | Plg |
| Synonyms | AI649309; Pg |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_008877 |
| ORF Size | 2436 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_008877.2, NP_032903.2 |
| RefSeq Size | 2771 bp |
| RefSeq ORF | 2439 bp |
| Locus ID | 18815 |
| UniProt ID | P20918 |
| Cytogenetics | 17 8.5 cM |
| Summary | Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_008877" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MC201050 | Plg (untagged) - Mouse plasminogen (Plg), (10ug) | 10 ug |
$744.00
|
|
| MR210779 | Plg (Myc-DDK-tagged) - Mouse plasminogen (Plg) | 10 ug |
$589.00
$744.00
|
|
| MR210779L3 | Lenti ORF clone of Plg (Myc-DDK-tagged) - Mouse plasminogen (Plg) | 10 ug |
$1,044.00
|
|
| MR210779L4 | Lenti ORF clone of Plg (mGFP-tagged) - Mouse plasminogen (Plg) | 10 ug |
$1,044.00
|
|
Citations
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