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Cfh (NM_009888) Mouse Untagged Clone

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SKU
MC224056
Cfh (untagged) - Mouse complement component factor h (Cfh), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
  $1,200.00
6 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Cfh
Synonyms Mud-1; NOM; Sas-1; Sas1
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC224056 representing NM_009888
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGTACAGCACAGATTTCTCTTGGAGTCAGTTGGTCCCAGAAAGATCCAAATTATGAGACTGTCAGCAA
GAATTATTTGGCTTATATTATGGACTGTTTGTGCAGCAGAAGATTGTAAAGGTCCTCCTCCAAGAGAAAA
TTCAGAAATTCTCTCAGGCTCGTGGTCAGAACAACTATATCCAGAAGGCACCCAGGCTACCTACAAATGC
CGCCCTGGATACCGAACACTTGGCACTATTGTAAAAGTATGCAAGAATGGAAAATGGGTGGCGTCTAACC
CATCCAGGATATGTCGGAAAAAGCCTTGTGGGCATCCCGGAGACACACCCTTTGGGTCCTTTAGGCTGGC
AGTTGGATCTCAATTTGAGTTTGGTGCAAAGGTTGTTTATACCTGTGATGATGGGTATCAACTATTAGGT
GAAATTGATTACCGTGAATGTGGTGCAGATGGGTGGATCAATGATATTCCACTATGTGAAGTTGTGAAGT
GTCTACCTGTGACAGAACTCGAGAATGGAAGAATTGTGAGTGGTGCAGCAGAAACAGACCAGGAATACTA
TTTTGGACAGGTGGTGCGGTTTGAATGCAATTCAGGCTTCAAGATTGAAGGACATAAGGAAATTCATTGC
TCAGAAAATGGCCTTTGGAGCAATGAAAAGCCACGATGTGTGGAAATTCTCTGCACACCACCGCGAGTGG
AAAATGGAGATGGTATAAATGTGAAACCAGTTTACAAGGAGAATGAAAGATACCACTATAAGTGTAAGCA
TGGTTATGTGCCCAAAGAAAGAGGGGATGCCGTCTGCACAGGCTCTGGATGGAGTTCTCAGCCTTTCTGT
GAAGAAAAGAGATGCTCACCTCCTTATATTCTAAATGGTATCTACACACCTCACAGGATTATACACAGAA
GTGATGATGAAATCAGATATGAATGTAATTATGGCTTCTATCCTGTAACTGGATCAACTGTTTCAAAGTG
TACACCCACTGGCTGGATCCCTGTTCCAAGATGTACCTTGAAACCATGTGAATTTCCACAATTCAAATAT
GGACGTCTGTATTATGAAGAGAGCCTGAGACCCAACTTCCCAGTATCTATAGGAAATAAGTACAGCTATA
AGTGTGACAACGGGTTTTCACCACCTTCTGGGTATTCCTGGGACTACCTTCGTTGCACAGCACAAGGGTG
GGAGCCTGAAGTCCCATGCGTCAGGAAATGTGTTTTCCATTATGTGGAGAATGGAGACTCTGCATACTGG
GAAAAAGTATATGTGCAGGGTCAGTCTTTAAAAGTCCAGTGTTACAATGGCTATAGTCTTCAAAATGGTC
AAGACACAATGACATGTACAGAGAATGGCTGGTCCCCTCCTCCCAAATGCATCCGTATCAAGACATGTTC
AGCATCAGATATACACATTGACAATGGATTTCTTTCTGAATCTTCTTCTATATATGCTCTAAATAGAGAA
ACATCCTATAGATGTAAGCAGGGATATGTGACAAATACTGGAGAAATATCAGGATCAATAACTTGCCTTC
AAAATGGATGGTCACCTCAACCCTCATGCATTAAGTCTTGTGATATGCCTGTATTTGAGAATTCTATAAC
TAAGAATACTAGGACATGGTTTAAGCTCAATGACAAATTAGACTATGAATGTCTCGTTGGATTTGAAAAT
GAATATAAACATACCAAAGGCTCTATAACATGTACTTATTATGGATGGTCTGATACACCCTCATGTTATG
AAAGAGAATGCAGTGTTCCCACTCTAGACCGAAAACTAGTCGTTTCCCCCAGAAAAGAAAAATACAGAGT
TGGAGATTTGTTGGAATTCTCCTGCCATTCAGGACACAGAGTTGGGCCAGATTCAGTGCAATGCTACCAC
TTTGGATGGTCTCCTGGTTTCCCTACATGTAAAGGTCAAGTAGCATCATGTGCACCACCTCTTGAAATTC
TTAATGGGGAAATTAATGGAGCAAAAAAAGTTGAATACAGCCATGGTGAAGTGGTGAAATATGATTGCAA
ACCTAGATTCCTACTGAAGGGACCCAATAAAATCCAGTGTGTTGATGGGAATTGGACAACCTTGCCTGTA
TGTATTGAGGAGGAGAGAACATGTGGAGACATTCCTGAACTTGAACATGGCTCTGCCAAGTGTTCTGTTC
CTCCCTACCACCATGGAGATTCAGTGGAGTTCATTTGTGAAGAAAACTTCACAATGATTGGACATGGGTC
AGTTTCTTGCATTAGTGGAAAATGGACCCAGCTTCCTAAATGTGTTGCAACAGACCAACTGGAGAAGTGT
AGAGTGCTGAAGTCAACTGGCATAGAAGCAATAAAACCAAAATTGACTGAATTTACGCATAACTCCACCA
TGGATTACAAATGTAGAGACAAGCAGGAGTACGAACGCTCAATCTGTATCAATGGAAAATGGGATCCTGA
ACCAAACTGTACAAGCAAAACATCCTGCCCTCCTCCACCGCAGATTCCAAATACCCAAGTGATTGAAACC
ACCGTGAAATACTTGGATGGAGAAAAATTATCTGTTCTTTGCCAAGACAATTACCTAACTCAGGACTCAG
AAGAAATGGTGTGCAAAGATGGAAGGTGGCAGTCATTACCTCGCTGCATTGAAAAAATTCCATGTTCCCA
GCCCCCTACAATAGAACATGGATCTATTAATTTACCCAGATCTTCAGAAGAAAGGAGAGATTCCATTGAG
TCCAGCAGTCATGAACATGGAACTACATTCAGCTATGTCTGTGATGATGGTTTCAGGATACCTGAAGAAA
ATAGGATAACCTGCTACATGGGAAAATGGAGCACTCCACCTCGCTGTGTTGGACTTCCTTGTGGACCTCC
ACCTTCAATTCCTCTTGGTACTGTTTCTCTTGAGCTAGAGAGTTACCAACATGGGGAAGAGGTTACATAC
CATTGTTCTACAGGCTTTGGAATTGATGGACCAGCATTTATTATATGCGAAGGAGGAAAGTGGTCTGACC
CACCAAAATGCATAAAAACGGATTGTGACGTTTTACCCACAGTTAAAAATGCCATAATAAGAGGAAAGAG
CAAAAAATCATATAGGACAGGAGAACAAGTGACATTCAGATGTCAATCTCCTTATCAAATGAATGGCTCA
GACACTGTGACATGTGTTAATAGTCGGTGGATTGGACAGCCAGTATGCAAAGATAATTCCTGTGTGGATC
CACCACATGTGCCAAATGCTACTATAGTAACAAGGACCAAGAATAAATATCTACATGGTGACAGAGTACG
TTATGAATGTAATAAACCTTTGGAACTATTTGGGCAAGTGGAAGTGATGTGTGAAAATGGGATATGGACA
GAAAAACCAAAGTGCCGAGACTCAACAGGGAAATGTGGGCCTCCTCCACCTATTGACAATGGAGACATCA
CCTCCTTGTCATTACCAGTATATGAACCATTATCATCAGTTGAATATCAATGCCAGAAGTATTATCTCCT
TAAGGGAAAGAAGACAATAACATGTAGAAATGGAAAGTGGTCTGAGCCACCAACATGCTTACATGCATGT
GTAATACCAGAAAACATTATGGAATCACACAATATAATTCTCAAATGGAGACACACTGAAAAGATTTATT
CCCATTCAGGGGAGGATATTGAATTTGGATGTAAATATGGATATTATAAAGCAAGAGATTCACCGCCATT
TCGTACAAAGTGCATTAATGGCACCATCAATTATCCCACTTGTGTATAA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_009888
Insert Size 3759 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_009888.3, NP_034018.2
RefSeq Size 4365 bp
RefSeq ORF 3759 bp
Locus ID 12628
UniProt ID P06909
Cytogenetics 1 F
Summary Glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. For example, interacts with CR3/ITGAM receptor and thereby mediates the adhesion of human neutrophils to different pathogens. In turn, these pathogens are phagocytosed and destroyed.UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_009888" in other vectors (4)
SKU Description Size Price
MG218690 Cfh (tGFP-tagged) - Mouse complement component factor h (Cfh), (10ug) 10 ug
$1,290.00
MR218690 Cfh (Myc-DDK-tagged) - Mouse complement component factor h (Cfh) 10 ug
$589.00 $1,090.00
MR218690L3 Lenti ORF clone of Cfh (Myc-DDK-tagged) - Mouse complement component factor h (Cfh) 10 ug
$1,390.00
MR218690L4 Lenti ORF clone of Cfh (mGFP-tagged) - Mouse complement component factor h (Cfh) 10 ug
$1,390.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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