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Adcy7 (NM_001109756) Mouse Untagged Clone

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SKU
MC223539
Adcy7 (untagged) - Mouse adenylate cyclase 7 (Adcy7), transcript variant 4, (10ug)
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ORF Plasmid:
Tag Free tGFP DDK
  $1,053.00
6 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Adcy7
Synonyms AA407758
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC223539 representing NM_001109756
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCCAGCCAAGGGGCGCTACTTCCTAAATGAGGGTGATGAAGGCCCCGACCAGGCAGCGCTCTATGAGA
AGTACCGGCTCACCAGCTTGCACGGGCCACTGCTGCTCTTGCTCCTCCTGGTGGCCGCGGCCACCTGCAT
TGCGCTCATCAGCATCGCCTTCAGTCATGAGGATCTCCGCAGACACCAGGTTGTCCTGGGCACTGCGTTC
CTCATGCTGACGCTGTTTGTGGCTCTCTATGTGCTGGTGTATGTCGAGTGCCTGGTGCAGCGGTGGCTGC
GGGCCTTGGCGCTACTCACCTGGGCTTGCCTCATGGTACTAGGCTCCGTGCTGATGTGGGACTCTTTGGA
GAATGAAGCCCATGCGTGGGAGCAGGTGCCTTTCTTCCTGTTTGTCGTCTTTGTGGTGTATGCACTACTG
CCTCTCAGCAGGAGGGCAGCCATCGTGGCAGGCGTGACCTCCACGGTCTCCCATCTCCTGGTGTTTGGAG
CTGTGACAAGAGCCTTCCAGACGTCCATGTCTAGCACTCAACTGGGGCTGCAGCTCCTGGCCAATGCCGT
TATCCTCCTGGGTGGGAACTTCACGGGTGCCTTCCACAAGCACCAGCTGCAGGACGCGTCCAGGGATCTC
TTTATCTACACCGTCAAATGCATCCAGATCCGTCGGAAGCTTCGTGTGGAGAAGCGCCAGCAGGAGAACC
TGCTTCTGTCAGTGCTCCCAGCACACATCTCCATGGGTATGAAGCTGGCCATCATTGAGCGCCTCAAAGA
GGGTGGTGACCGACACTACATGCCCGACAACAACTTTCACAGCCTCTATGTCAAGCGGCACCAGAATGTC
AGCATCTTGTATGCAGACATCGTGGGCTTCACGAGGCTGGCCAGCGACTGCTCTCCCAAGGAGCTGGTGG
TGGTGCTCAACGAGCTGTTTGGGAAGTTTGACCAGATTGCTAAGGCCAATGAGTGCATGCGGATCAAGAT
CCTGGGTGACTGTTACTACTGCGTGTCAGGCCTGCCCGTGTCGCTGCCCACACATGCCCGCAACTGTGTG
AAGATGGGTCTGGACATCTGCGAGGCCATTAAGCAGGTGCGTGAGGCCACGGGCGTGGACATCAGCATGC
GTGTGGGCATTCACTCCGGGAATGTGCTATGTGGGGTCATCGGGCTCCGTAAGTGGCAGTATGATGTGTG
GTCCCATGATGTGTCCCTGGCCAACAGGATGGAGGCAGCTGGAGTCCCTGGCCGGGTGCACATCACAGAG
GCAACATTGAATCACCTGGACAAGGCATATGAGGTGGAGGATGGGCATGGGGAGCAGCGAGACCCCTATC
TGAAAGAGATGAACATCCGAACCTACCTGGTGATCGATCCCCGGAGCCAGCAGCCACCCCCACCCAGCCA
CCACCTCTCCAAGCCCAAGGGGGACGCAACTCTGAAGATGCGGGCTTCAGTGCGTGTAACCCGCTATCTG
GAGTCTTGGGGGGCAGCAAGGCCCTTTGCACACCTCAACCACCGGGAGAGTGTGAGCAGCAGTGAGACCC
CCATCTCCAATGGACGGAGGCAGAAGGCCATTCCTCTGCGTCGACACCGTGCCCCTGATAGGAGTGCATC
TCCCAAGGGGCGCTTGGAAGATGACTGTGATGACGAGATGCTGTCAGCCATTGAGGGTCTCAGCTCCACC
AGGCCCTGCTGCTCCAAGTCTGATGACTTCCACACCTTTGGTCCCATCTTCTTGGAGAAGGGCTTTGAGC
GTGAGTACCGCCTGGTGCCCATCCCCCGGGCTCGCTACGACTTCGCCTGTGCCAGCCTTGTCTTCGTCTG
CATCCTGCTTGTCCACCTTCTAGTGATGCCCAGGATGGCAACTCTGGGTGTGTCCTTTGGGTTGGTGGCC
TGCCTGCTGGGGCTGGTTCTGAGTTTCTGCTTTGCTACTGAGTTCTCGAGGTGCTTTCCATCCCGAAGTA
CACTCCAGGCCATCTCGGAGAGCGTGGAGACGCAGCCCCTGGTCAGGCTTGTCCTGGTTGTGCTGACTGT
TGGCAGCCTACTGACTGTCGCCATCATTAACATGCCACTGACGCTTAACCCAGGCCCAGAGCAGCCTGGA
GACAACAAGACAAGCCCACTGGCTGCACAGAACAGAGTTGGGACCCCATGTGAGCTCCTCCCGTACTACA
CCTGCAGCTGCATCCTGGGCTTCATTGCATGCTCTGTTTTCCTGCGGATGAGCCTAGAGCTGAAGGCCAT
GCTGCTGACAGTGGCCTTGGTGGCCTACCTGCTGCTCTTCAACCTCTCCCCATGCTGGCACGTCTCAGGC
AACAGCACTGAGACCAACGGGACACAAAGGACACGGCTGCTCCTGTCTGATGCACAAAGCATGCCCAGCC
ACACCCTTGCTCCGGGGGCTCGGGAGACTGCCCCTTCTCCCAGTTATTTAGAGAGAGACCTGAAGATCAT
GGTTAACTTCTACCTGATCCTGTTCTATGCCACCCTCATCTTGCTGTCTAGACAGATTGACTACTACTGC
CGCTTGGACTGTCTGTGGAAGAAGAAGTTCAAAAAGGAGCACGAGGAGTTTGAAACAATGGAGAATGTGA
ACCGCCTCCTCCTGGAGAATGTGCTGCCGGCGCACGTGGCTGCCCACTTCATTGGGGACAAGGCAGCAGA
GGATTGGTACCATCAATCTTATGACTGTGTCTGTGTCATGTTTGCATCCGTTCCGGACTTCAAAGTGTTC
TACACTGAGTGTGATGTCAACAAAGAAGGACTGGAGTGCCTTCGACTGCTGAATGAGATAATTGCTGATT
TTGACGAGCTCCTGCTGAAGCCCAAGTTTAGTGGTGTGGAGAAGATCAAGACCATTGGCAGCACCTACAT
GGCGGCAGCAGGGCTCAGTGCCCCCTCAGGACATGAGAACCAGGACCTGGAGCGGAAGCACGTGCACATC
GGAGTCTTGGTAGAATTTAGCATGGCCCTGATGAGCAAGCTGGATGGGATCAACAGGCACTCCTTCAACT
CCTTCCGCCTCCGAGTCGGCATAAACCACGGGCCTGTGATTGCTGGAGTGATTGGAGCACGCAAGCCTCA
GTATGACATCTGGGGAAACACAGTCAATGTTGCCAGCCGCATGGAGAGCACCGGAGAGCTTGGGAAAATC
CAGGTTACCGAAGAGACATGCACTATCCTCCAGGGACTCGGATATTCGTGTGAATGCCGTGGGCTGATCA
ACGTCAAAGGCAAAGGGGAACTGCGGACTTACTTTGTATGTACAGACACTGCCAAGTTTCAAGGGCTGGG
GCTAAACTGA

AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
TGGATTACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-RsrII |
ACCN NM_001109756
Insert Size 3300 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001109756.1, NP_001103226.1
RefSeq Size 5937 bp
RefSeq ORF 3300 bp
Locus ID 11513
UniProt ID P51829
Cytogenetics 8 43.06 cM
Summary Catalyzes the formation of cAMP in response to activation of G protein-coupled receptors (Probable). Functions in signaling cascades activated namely by thrombin and sphingosine 1-phosphate and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G alpha protein with GNA13 (PubMed:18541530). Also, during inflammation, mediates zymosan-induced increase intracellular cAMP, leading to protein kinase A pathway activation in order to modulate innate immune responses through heterotrimeric G proteins G(12/13) (PubMed:23178822). Functions in signaling cascades activated namely by dopamine and C5 alpha chain and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G protein with G beta:gamma complex (By similarity). Functions, through cAMP response regulation, to keep inflammation under control during bacterial infection by sensing the presence of serum factors, such as the bioactive lysophospholipid (LPA) that regulate LPS-induced TNF-alpha production. However, it is also required for the optimal functions of B and T cells during adaptive immune responses by regulating cAMP synthesis in both B and T cells (PubMed:20505140).UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
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Documents
Resources
"NM_001109756" in other vectors (4)
SKU Description Size Price
MG226308 Adcy7 (tGFP-tagged) - Mouse adenylate cyclase 7 (Adcy7) transcript variant 4, (10ug) 10 ug
$1,157.00
MR226308 Adcy7 (Myc-DDK-tagged) - Mouse adenylate cyclase 7 (Adcy7), transcript variant 4 10 ug
$589.00 $957.00
MR226308L3 Lenti ORF clone of Adcy7 (Myc-DDK-tagged) - Mouse adenylate cyclase 7 (Adcy7), transcript variant 4 10 ug
$1,257.00
MR226308L4 Lenti ORF clone of Adcy7 (mGFP-tagged) - Mouse adenylate cyclase 7 (Adcy7), transcript variant 4 10 ug
$1,257.00

file-alt Citations

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