Ranbp9 (NM_019930) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Ranbp9 |
| Synonyms | IBAP-1; Ibap1; RanBPM |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_019930 |
| Insert Size | 2133 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_019930.2, NP_064314.2 |
| RefSeq Size | 3064 bp |
| RefSeq ORF | 2133 bp |
| Locus ID | 56705 |
| UniProt ID | P69566 |
| Cytogenetics | 13 A4 |
| Summary | May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways. Acts as a mediator of cell spreading and actin cytoskeleton rearrangement. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.UniProtKB/Swiss-Prot Function |
Reviews
Documents
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| FAQs |
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Resources
"NM_019930" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG223278 | Ranbp9 (tGFP-tagged) - Mouse RAN binding protein 9 (Ranbp9), (10ug) | 10 ug |
$850.00
|
|
| MR223278 | Ranbp9 (Myc-DDK-tagged) - Mouse RAN binding protein 9 (Ranbp9) | 10 ug |
$589.00
$650.00
|
|
| MR223278L3 | Lenti ORF clone of Ranbp9 (Myc-DDK-tagged) - Mouse RAN binding protein 9 (Ranbp9) | 10 ug |
$950.00
|
|
| MR223278L4 | Lenti ORF clone of Ranbp9 (mGFP-tagged) - Mouse RAN binding protein 9 (Ranbp9) | 10 ug |
$950.00
|
|
Citations
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