Aplp2 (NM_009691) Mouse Untagged Clone

SKU MC220563

Aplp2 (untagged) - Mouse amyloid beta (A4) precursor-like protein 2 (Aplp2), transcript variant 3, (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Aplp2
• Synonyms: AI790698; APLP-2; CDEBP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC220563 representing NM_009691; Red=Cloning site Blue=ORF Orange=Stop codon; ; TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC; GCCGCGATCGCC; ; ATGGCGGCCACCGGGACCGCGGCCGCTGCGGCCACCGGCAAGCTTCTTGTCCTGCTGCTGCTCGGGCTCA; CGGCGCCCGCTGCGGCTCTGGCTGGCTACATAGAGGCTCTTGCAGCCAATGCTGGAACAGGCTTCGCTGT; TGCTGAGCCTCAGATTGCGATGTTCTGTGGGAAGCTGAATATGCATGTGAACATTCAGACTGGCAAATGG; GAGCCTGACCCAACAGGCACCAAGAGCTGCCTTGGAACAAAGGAGGAGGTTCTTCAGTACTGCCAGGAGA; TATATCCAGAGCTGCAGATCACAAATGTGATGGAAGCAAACCAGCCAGTCAATATTGATAGTTGGTGCCG; AAGGGACAAAAGGCAGTGCAAGAGTCACATTGTTATACCATTCAAGTGTCTTGTGGGTGAATTTGTAAGT; GATGTCCTGCTAGTTCCAGATAACTGCCAGTTTTTCCACCAAGAGCGGATGGAGGTGTGTGAGAAGCACC; AGCGCTGGCACACGTTAGTCAAGGAGGCATGTCTGACTGAGGGGCTGACCTTATATAGCTATGGCATGCT; GCTGCCCTGCGGGGTAGACCAGTTCCATGGCACCGAGTATGTGTGCTGCCCTCAGACAAAGACTGTTGAC; TCGGACTCGACTATGTCCAAAGAAGAGGAGGAAGAGGAAGAGGATGAAGAGGACGAAGAGGAAGACTATG; ATCTTGATAAAAGTGAATTTCCTACTGAAGCAGATTTGGAAGACTTCACAGAAGCAGCAGCAGATGAGGA; AGAAGAGGATGAGGAGGAAGGGGAGGAAGTGGTGGAAGACCGTGACTACTACTATGACCCCTTTAAAGGA; GACGATTACAATGAGGAGAATCCAACCGAACCCAGCAGCGAGGGCACCATTTCAGACAAGGAGATTGTTC; ACGATGTTAAAGTTCCCCCGACTCCCCTGCCAACCAATGATGTTGATGTGTATTTTGAGACCTCAGCGGA; TGATAATGAGCACGCCCGCTTCCAGAAGGCTAAGGAACAGCTGGAAATTCGACATCGAAACCGAATGGAC; AGGGTAAAGAAGGAATGGGAAGAGGCAGAACTTCAAGCCAAGAACCTCCCCAAGACAGAAAGACAGACCC; TCATCCAGCATTTCCAAGCTATGGTTAAAGCTTTAGAGAAAGAAGCAGCCAGTGAGAAGCAGCAGCTTGT; GGAAACCCATCTGGCCCGAGTAGAAGCCATGCTGAATGACCGCCGACGCATAGCTCTGGAAAATTACCTG; GCTGCCCTGCAGTCTGACCCACCTCGGCCACATCGCATTCTTCAAGCTCTTCGTCGTTACGTCCGTGCTG; AGAACAAAGATCGCCTGCATACCATTCGTCATTACCAACACGTGTTGGCTGTTGACCCAGAAAAGGCCGC; CCAGATGAAATCCCAGGTGATGACACACCTCCATGTGATTGAAGAAAGAAGGAACCAAAGTCTTTCTCTT; CTGTACAAAGTTCCTTATGTTGCTCAAGAAATTCAAGAGGAAATTGATGAGCTCCTTCAGGAACAGCGAG; CGGATATGGACCAATTTACCTCCTCCATCTCAGAGAACCCTGTGGATGTCCGGGTGAGCTCTGAGGAGAG; TGAGGAGATCCCGCCGTTCCACCCTCTCCATCCCTTCCCATCCTTGTCTGAGAATGAAGGCTCTGGAATG; GCAGAACAAGACGGGGGACTGATTGGTGCAGAAGAAAAAGTGATTAACAGCAAGAATAAAATGGATGAAA; ATATGGTCATTGACGAGACTCTGGATGTTAAGGAAATGATTTTCAATGCTGAGAGAGTTGGAGGCCTTGA; GGAAGAGCCGGAATCGGTGGGACCTTTAAGGGAGGATTTCAGTTTGAGCAGCAATGCCCTTATTGGCTTG; CTGGTTATCGCAGTGGCCATTGCTACGGTCATCGTTATCAGCCTGGTGATGCTGAGGAAGAGGCAGTACG; GCACCATCAGCCACGGGATTGTGGAGGTTGACCCAATGCTCACCCCAGAAGAGCGTCACCTGAACAAGAT; GCAGAACCATGGTTATGAAAACCCAACCTACAAATACCTGGAGCAGATGCAGATTTAA; ; ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT; ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_009691
• Insert Size: 2088 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_009691.2, NP_033821.1
• RefSeq Size: 3490 bp
• RefSeq ORF: 2088 bp
• Locus ID: 11804
• Cytogenetics: 9 16.66 cM
• Summary: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein (By similarity). Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts.[UniProtKB/Swiss-Prot Function]; Transcript Variant: This variant (3) lacks two alternate in-frame exons compared to variant 4. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform d.