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Socs5 (NM_019654) Mouse Untagged Clone

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SKU
MC217592
Socs5 (untagged) - Mouse suppressor of cytokine signaling 5 (Socs5), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free DDK
AAV Particle:
DDK
  $550.00
3 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Socs5
Synonyms 1810018L08Rik; Cish5; mKIAA0671
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC217592 representing NM_019654
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGATAAAGTGGGGAAAATGTGGAACAACTTAAAATACAGATGCCAGAATCTCTTCAGCCACGAGGGAG
GAAGCCGTAATGAGAACGTGGAGATGAACCCCAACAGATGTCCGTCTGTCAAAGAGAAAAGCATCAGTCT
GGGAGAGGCAGCTCCCCAGCAAGAGAGCAGTCCCTTAAGAGAAAATGTTGCCTTACAGCTGGGACTGAGC
CCTTCCAAGACCTTTTCCAGGCGGAACCAAAACTGTGCCGCAGAGATCCCTCAAGTGGTTGAAATCAGCA
TCGAGAAAGACAGTGACTCGGGTGCCACCCCAGGAACGAGGCTTGCACGGAGAGACTCCTACTCGCGGCA
CGCCCCGTGGGGAGGAAAGAAGAAACATTCCTGTTCCACAAAGACCCAGAGTTCATTGGATACCGAGAAA
AAGTTTGGTAGAACTCGAAGCGGCCTTCAGAGGCGAGAGCGGCGCTATGGAGTCAGCTCCATGCAGGACA
TGGACAGCGTTTCTAGCCGCGCGGTCGGGAGCCGCTCCCTGAGGCAGAGGCTCCAGGACACGGTGGGTTT
GTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCACTCTTTTCCAATAAAAGAAAAATACATCTT
TCTGAATTAATGCTGGAGAAATGCCCTTTTCCTGCTGGCTCGGATTTAGCACAAAAGTGGCATTTGATTA
AACAGCATACCGCCCCTGTGAGCCCACACTCAACATTTTTTGATACATTTGATCCATCACTGGTGTCTAC
AGAAGATGAAGAAGATAGGCTTCGCGAGAGAAGACGGCTTAGTATCGAAGAAGGGGTGGATCCCCCTCCC
AACGCACAAATACACACCTTTGAAGCTACTGCACAGGTCAACCCATTGTATAAGCTGGGACCAAAGTTAG
CTCCTGGGATGACAGAGATAAGTGGAGATGGTTCTGCAATTCCACAAACGAATTGTGACTCAGAAGAGGA
TTCAACCACCCTATGTCTGCAGTCACGGAGGCAGAAGCAGCGCCAGGTGTCCGGGGACAGCCACGCGCAC
GTTAGCAGACAGGGAGCTTGGAAAGTTCATACGCAGATCGATTACATACACTGCCTCGTGCCAGATTTGC
TTCAGATCACAGGGAATCCCTGTTACTGGGGCGTGATGGACCGATACGAGGCCGAAGCCCTTCTAGAAGG
GAAACCGGAAGGCACGTTCTTGCTCAGGGACTCTGCACAGGAGGACTACCTCTTCTCTGTGAGCTTCCGC
CGCTACAACAGGTCTCTGCACGCCCGGATCGAGCAGTGGAACCACAACTTCAGCTTCGATGCCCATGACC
CCTGCGTGTTTCACTCCTCCACTGTCACGGGGCTTCTCGAACACTATAAAGACCCCAGCTCTTGCATGTT
TTTTGAACCGTTGCTAACGATATCACTGAATAGAACTTTCCCTTTCAGCCTGCAGTATATCTGCCGCGCA
GTGATCTGCAGATGCACTACGTATGATGGGATTGACGGGCTCCCGCTACCGTCGATGTTACAGGATTTTT
TAAAAGAGTATCATTATAAACAAAAAGTTAGGGTTCGCTGGTTAGAACGAGAACCAGTCAAAGCAAAGTA
A

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_019654
Insert Size 1611 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_019654.2, NP_062628.2
RefSeq Size 4460 bp
RefSeq ORF 1611 bp
Locus ID 56468
UniProt ID O54928
Cytogenetics 17 E4
Summary SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in the regulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiation into the Th2 phenotype. Can also partially inhibit IL6 and LIF signaling.UniProtKB/Swiss-Prot Function
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"NM_019654" in other vectors (3)
SKU Description Size Price
MR208589 Socs5 (Myc-DDK-tagged) - Mouse suppressor of cytokine signaling 5 (Socs5) 10 ug
$289.00 $500.00
MR208589L3 Lenti ORF clone of Socs5 (Myc-DDK-tagged) - Mouse suppressor of cytokine signaling 5 (Socs5) 10 ug
$800.00
MR208589L4 Lenti ORF clone of Socs5 (mGFP-tagged) - Mouse suppressor of cytokine signaling 5 (Socs5) 10 ug
$800.00

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