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Tradd (NM_001033161) Mouse Untagged Clone

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SKU
MC211207
Tradd (untagged) - Mouse TNFRSF1A-associated via death domain (Tradd), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $330.00
4 Weeks*
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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Tradd
Synonyms 9130005N23Rik; AA930854
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC211207 representing NM_001033161
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCAGCCGGTCAGAATGGCCACGAGGAGTGGGTGGGCAGTGCATACCTGTTTTTGGAGTCTGCGGTAG
ACAAGGTGATCCTGTCTGAAGCCTACACGGATCCCAAGAAGAAGGTGGCAATATACAAGGCTCTGCAGAC
TGCACTGTCAGAGAGTGGGGACAGCTCTGACGTACTGCAGATACTCAAGATCCACTGCAGCGACCCTCAG
CTCATCGTCCAGTTGCGGTTCTGCGGGCGCGTGCTGTGCGGCCGCTTCCTCCAAGCCTACCGCGAGGGGG
CGCTGCGCACCGCGCTGCAGAGGTGCATGGCCCCGGCGCTTGCCCAGGAAGCGCTGCGGTTGCAGCTGGA
GTTGCGTGCAGGTGCGGAGCAGCTGGACAGTTGGCTGACTGATGAAGAGCGCTGTTTGAATTACATCTTA
GCCCAGAAGCCCGACCGGCTCAGGGACGAGGAACTCGCGGAGCTGGAGGATGAGCTCTGCAAACTGACGT
GTGACTGCACTGGCCAGGGTGGAGCCATACAGGTAGCTTCTGCAGGTTCGAAGTTCCCGGTTTCCTCTCC
GACCGAGGAGAAACCACTGCCGGCCGCCTGCCAGACTTTTCTGTTCCACGGGCAGCTCGTAGTGAACCGG
CCACTGACTCTTCAAGACCAGCAGACGTTTGCGCGCTCGGTGGGTCTCAAGTGGCGCAGGGTGGGGCGCT
CGCTGCAGCGTAACTGTCGGGCACTGAGAGATCCTGCCCTCGACTCGCTGGCCTACGAGTATGAGCGTGA
TGGGCTATACGAGCAGGCCTTCCAGCTGCTGCGCCGTTTCATGCAAGCCGAGGGCCGCCGTGCCACACTG
CAGCGCCTGGTGGAGGCGCTGGAGGAGAACGAACTCACTAGTCTAGCAGAGGATCTGTTGGGCCAGGCGG
AGCCGGATGGCGGCCTGGCCTAA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_001033161
Insert Size 933 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001033161.2, NP_001028333.1
RefSeq Size 1385 bp
RefSeq ORF 933 bp
Locus ID 71609
UniProt ID Q3U0V2
Cytogenetics 8 53.04 cM
Summary Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.UniProtKB/Swiss-Prot Function
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"NM_001033161" in other vectors (4)
SKU Description Size Price
MG223646 Tradd (tGFP-tagged) - Mouse TNFRSF1A-associated via death domain (Tradd), (10ug) 10 ug
$500.00
MR223646 Tradd (Myc-DDK-tagged) - Mouse TNFRSF1A-associated via death domain (Tradd) 10 ug
$289.00 $300.00
MR223646L3 Lenti ORF clone of Tradd (Myc-DDK-tagged) - Mouse TNFRSF1A-associated via death domain (Tradd) 10 ug
$600.00
MR223646L4 Lenti ORF clone of Tradd (mGFP-tagged) - Mouse TNFRSF1A-associated via death domain (Tradd) 10 ug
$600.00

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