OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Mob1b (NM_026735) Mouse Untagged Clone

Be the first to review this product
SKU
MC210729
Mob1b (untagged) - Mouse MOB1, Mps One Binder kinase activator-like 1A (yeast) (Mobkl1a), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
  $480.00
3 Weeks*
Bulk Requests & Clone Modifications

Frequently Bought Together (2)

PRIMER Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
100 pmol
$59.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "Mob1b or NM_026735"

Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Mob1b
Synonyms 1110003E08Rik; AU015450; B230364F10; Mobkl1a
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC210729 representing NM_026735
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGAGCTTCTTGTTTGGTAGTCGCTCTTCTAAAACTTTTAAACCAAAGAAGAACATACCAGAGGGGTCTC
ACCAGTATGAACTCTTAAAGCATGCGGAAGCCACACTGGGCAGCGGCAACCTACGGATGGCTGTCATGCT
TCCCGAGGGAGAGGATCTGAATGAGTGGGTTGCAGTTAACACTGTGGATTTTTTCAATCAAATCAATATG
CTTTATGGAACCATCACAGACTTCTGTACAGAGGAGAGCTGTCCGGTGATGTCAGCTGGACCAAAATATG
AATATCACTGGGCAGATGGAACAAACATAAAAAAGCCTATTAAGTGTTCTGCACCAAAGTATATTGATTA
CTTGATGACTTGGGTTCAGGACCAGCTGGATGATGAGACATTATTTCCATCAAAAATTGGTGTTCCATTC
CCGAAGAATTTCATGTCAGTGGCAAAAACAATACTCAAACGACTCTTTAGAGTTTATGCTCATATTTATC
ACCAACATTTTGACCCTGTGATCCAGCTTCAGGAGGAAGCACATCTCAATACATCTTTCAAGCACTTTAT
TTTTTTCGTTCAGGAGTTCAACCTTATTGACAGACGAGAGTTGGCACCACTGCAAGAGCTGATTGAAAAA
CTCACCTCAAAGGACAGATAA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_026735
Insert Size 651 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_026735.2, NP_081011.1
RefSeq Size 3171 bp
RefSeq ORF 651 bp
Locus ID 68473
UniProt ID Q8BPB0
Cytogenetics 5 E1
Summary Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L (By similarity).UniProtKB/Swiss-Prot Function
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
"NM_026735" in other vectors (4)
SKU Description Size Price
MG218570 Mob1b (tGFP-tagged) - Mouse MOB1 Mps One Binder kinase activator-like 1A (yeast) (Mobkl1a), (10ug) 10 ug
$680.00
MR218570 Mob1b (Myc-DDK-tagged) - Mouse MOB1, Mps One Binder kinase activator-like 1A (yeast) (Mobkl1a) 10 ug
$480.00
MR218570L3 Lenti ORF clone of Mob1b (Myc-DDK-tagged) - Mouse MOB1, Mps One Binder kinase activator-like 1A (yeast) (Mobkl1a) 10 ug
$780.00
MR218570L4 Lenti ORF clone of Mob1b (mGFP-tagged) - Mouse MOB1, Mps One Binder kinase activator-like 1A (yeast) (Mobkl1a) 10 ug
$780.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products