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Arnt (NM_001037737) Mouse Untagged Clone

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SKU
MC205717
Arnt (untagged) - Mouse aryl hydrocarbon receptor nuclear translocator (Arnt), transcript variant 1, (10ug)
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ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $725.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Arnt
Synonyms bHLHe2; D3Ertd557e; Drnt; ESTM42; Hif1b; mKIAA4051; W08714
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC012870
GCGGCGGTAAGGTGCCTAATCTGCGGAGTGGCTCTTCCCTCCCCTCCCCCAGCTCGGTGGCGGCTGCCCC TCCCACCGAGGGTGGCGCAGGGACGGTGCCATCTCGACCATGGCGGCGACTACAGCTAACCCAGAAATGA CATCAGATGTACCATCGCTGGGTCCCACCATTGCTTCTGGAAACCCTGGACCTGGGATTCAAGGTGGAGG AGCTGTTGTACAGAGGGCTATTAAGCGACGGTCAGGGCTGGATTTTGATGATGAAGTAGAAGTGAACACT AAATTTTTGAGATGCGATGATGACCAGATGTGTAATGACAAAGAGCGGTTTGCCAGGTCGGATGATGAGC AGAGCTCTGCGGATAAAGAGAGACTTGCCAGGGAAAATCATAGTGAAATAGAACGGCGGCGACGGAACAA GATGACAGCTTACATCACAGAACTGTCAGACATGGTACCTACATGTAGTGCCCTGGCTCGAAAACCAGAC AAGCTAACCATCTTACGCATGGCCGTTTCTCACATGAAGTCCTTGAGGGGAACTGGCAACACATCTACTG ATGGCTCCTACAAGCCATCTTTCCTCACTGATCAGGAACTGAAACATTTGATCTTGGAGGCAGCAGATGG CTTTCTGTTTATTGTCTCCTGTGAGACTGGACGGGTGGTGTATGTCTCTGACTCAGTGACTCCCGTTTTG AACCAGCCACAGTCTGAATGGTTCGGGAGCACACTGTATGATCAGGTGCACCCAGATGATGTGGATAAAC TTCGAGAGCAGCTCTCTACATCAGAAAATGCCCTAACAGGGCGGGTCCTGGATCTGAAGACTGGAACAGT GAAAAAGGAAGGCCAGCAGTCTTCCATGAGGATGTGCATGGGCTCACGAAGGTCGTTCATCTGCCGCATG AGGTGTGGTACTAGCTCCGTGGACCCTGTTTCCATGAATAGACTGAGCTTTTTGAGGAACAGATGCAGGA ATGGGCTTGGCTCTGTGAAGGAAGGAGAACCTCACTTTGTGGTAGTCCACTGCACAGGCTACATCAAGGC CTGGCCACCAGCAGGTGTCTCCCTCCCAGATGATGACCCAGAGGCTGGCCAGGGGAGCAAATTCTGCCTA GTGGCCATTGGCAGGCTGCAGGTAACTAGTTCTCCCAACTGTACAGACATGAGTAACATTTGTCAGCCAA CAGAGTTCATCTCCCGACACAACATTGAAGGGATATTCACTTTTGTAGACCATCGTTGTGTGGCTACTGT TGGCTACCAGCCACAGGAGCTCTTAGGGAAGAATATTGTAGAATTTTGTCATCCTGAAGACCAACAACTT CTAAGAGACAGCTTTCAGCAGGTGGTGAAATTAAAAGGTCAGGTGCTGTCCGTCATGTTCCGATTCCGAT CTAAGACCCGAGAATGGCTGTGGATGAGAACGAGCTCCTTTACCTTCCAAAACCCTTATTCAGATGAAAT TGAGTATATTATCTGCACCAACACCAATGTGAAGAACTCTAGCCAGGAACCACGGCCTACACTGTCCAAC ACCATCCCAAGGTCACAGCTAGGTCCGACAGCCAATTTATCCCTAGAGATGGGTACAGGGCAGCTGCCAT CCAGGCAGCAGCAGCAGCAGCACACAGAACTGGATATGGTACCAGGAAGAGATGGGCTGGCCAGCTATAA TCATTCCCAGGTTTCTGTCCAGCCTGTGGCAAGTGCAGGATCAGAACACAGCAAGCCCCTTGAGAAGTCA GAAGGTCTCTTTGCACAGGACAGAGATCCAAGGTTTCCAGAAATCTATCCCAGCATCACTGCAGATCAGA GTAAAGGCATCTCCTCCAGCACTGTCCCTGCCACCCAACAGCTGTTCTCCCAGGGCAGCTCATTCCCTCC TAACCCCCGGCCGGCAGAGAATTTCAGGAATAGTGGTCTTACCCCTCCTGTAACCATTGTCCAGCCATCA TCTTCTGCAGGGCAGATACTGGCCCAGATTTCACGTCACTCCAACCCTGCCCAGGGATCAGCGCCGACCT GGACCTCTAGCTCCCGCCCAGGCTTTGCCGCCCAGCAGGTGCCCACCCAGGCTACAGCCAAGACTCGTTC TTCCCAATTTGGTGTGAACAACTTTCAGACTTCTTCCTCCTTCAGTGCTATGTCTCTTCCGGGTGCTCCC ACTGCCTCATCTGGTACTGCTGCCTACCCTGCTCTCCCCAACCGTGGCTCCAACTTTCCTCCTGAGACTG GACAGACCACAGGACAGTTCCAGGCCCGGACAGCAGAGGGCGTGGGTGTCTGGCCACAGTGGCAGGGCCA GCAGCCCCATCATCGGTCTAGTTCCAGTGAGCAGCATGTTCAGCAGACACAAGCACAAGCACCTAGCCAG CCTGAGGTCTTTCAAGAAATGCTGTCCATGCTGGGAGACCAAAGCAACACCTACAACAATGAAGAATTTC CTGATCTAACTATGTTTCCCCCCTTTTCCGAATAGAACTATTGGGGTGAGGATAAGGGTGGGGGGAAATC ACTGTTTGTTTTTAAAAGCAAATCTTTTGTAAACAGAATAAAAGTTCCTCTCCCTTCCCTTCCCTCACCC CTGATATGTACCCTTTCCACCCCTTGACTTGCTGAAGAAACGTTATAGAAGAAATTAAATGAATTTCCCA GGCAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI |
ACCN NM_001037737
Insert Size 2376 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC012870, AAH12870
RefSeq Size 2691 bp
RefSeq ORF 2376 bp
Locus ID 11863
UniProt ID P53762
Cytogenetics 3 40.74 cM
Summary Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (PubMed:26245371, PubMed:27782878). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28602820).UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (a).
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Documents
Resources
"NM_001037737" in other vectors (4)
SKU Description Size Price
MG210673 Arnt (tGFP-tagged) - Mouse aryl hydrocarbon receptor nuclear translocator (Arnt), transcript variant 1 10 ug
$925.00
MR210673 Arnt (Myc-DDK-tagged) - Mouse aryl hydrocarbon receptor nuclear translocator (Arnt), transcript variant 1 10 ug
$589.00 $725.00
MR210673L3 Lenti ORF clone of Arnt (Myc-DDK-tagged) - Mouse aryl hydrocarbon receptor nuclear translocator (Arnt), transcript variant 1 10 ug
$1,025.00
MR210673L4 Lenti ORF clone of Arnt (mGFP-tagged) - Mouse aryl hydrocarbon receptor nuclear translocator (Arnt), transcript variant 1 10 ug
$1,025.00

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