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Gm2a (NM_010299) Mouse Untagged Clone

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SKU
MC205674
Gm2a (untagged) - Mouse GM2 ganglioside activator protein (Gm2a), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $300.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Gm2a
Synonyms AA408702; AW215435; GM2-AP; SAP-3
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC004651
GGCAGCCGTGAGTCGCATTGCCTAGACCGACACGGAGGACCATCGCCATGCACCGTCTACCGCTGCTGCT CCTGCTGGGCTTGCTGCTCGCAGGCTCCGTCGCCCCTGCGCGCCTCGTCCCGAAGCGCCTTTCCCAACTT GGTGGCTTCTCCTGGGATAACTGTGATGAAGGAAAGGACCCTGCAGTGATCAAAAGCCTCACGATCCAAC CTGACCCCATTGTGGTTCCTGGAGATGTAGTCGTCAGCCTTGAGGGCAAGACCAGCGTTCCCCTCACTGC TCCTCAGAAGGTGGAGCTCACCGTGGAGAAGGAAGTGGCTGGCTTCTGGGTCAAGATTCCTTGTGTAGAA CAGCTAGGCAGCTGTAGCTACGAGAACATCTGTGACCTGATAGACGAATACATTCCTCCTGGAGAGAGCT GCCCAGAGCCCCTGCACACCTACGGGCTGCCCTGCCACTGTCCCTTCAAGGAAGGTACCTACTCACTACC CACGAGCAACTTCACAGTGCCTGACCTAGAGCTACCGAGCTGGCTGAGCACAGGCAACTACCGCATCCAG AGTATCTTGAGCAGTGGTGGGAAGCGCCTGGGCTGCATCAAGATTGCTGCCTCTCTCAAGGGCAGATAAC CTGGCAGCAGCCACCACAGAATGAAGGGGCACCAGCACGGCAGGCCTCTTCTTCTGTGTTCCGGTGCCCA GGCCTGCCTGCCTCTAACTCTATCCTCCTACGGTTCTCTACCCTCTCTGGAAATCATTGCAACCTGACCT GAGGGAGGATGGACCAGGCCCAACATCTGATGGGCTGTAAGCCATGCTCCTTTGCACCCCTACCAACTTT CTAAGAATTTCTTTCGTATCCAAAACAGTCAAGGAATGGGAACCAACATGTTTGGGAATCCTAAGGTCAA AACTGGCCCAACCTGGACCTCCTGGAGTTATGCTCACCCCACTTCTTTGTTTTAGTCACCAACTTTAAAA CCAGGATAACCGTATTAATTTCTCATTCCATCCTGAGCCTCTCTTCCTGCAAAGAGGTCTAGGTAGTCAG TCTTGGGTCCCTCTATTAACTTCTGTGATTAACTGCATTCTCTTTGCAACTTAACTTGTCAACACTGGGG CTGACAGATCCTGAAGAGGCAGGGTGGTGTGTGACAGAAACCTGTGAGAGTTATTGTTGGGCATGCTCCA GTAACCCTTGGCAAAGCACAGGTACCTGTAGGGCCAAGCCGAAGACCTAGGGAGGCACAGCAATCACTTC TGGGAGCGATGCCCATTTTTCCTTTTTCCTTTTTTTTTTTTTTTTTTTTTGGTATGATGCCTTCAAGAAT GGGATGGCATTCCTTATACCTGACAAGAAACAACCAAAAAAACCAATAGCACATGTGCTCTGGTGCCAGG TGGCCAGGGTCTGGAATGGCATATCTAGTTCTAAAGAGGTGCAGTCCCCTGCAAGTTCCATGTAAGGAAT GTTGCCAGATATTTGCAACATTTTTCTTCCTTAGGCCCCAAACCCAGCCGTTTATATGAAATTGTAGAAT TTTTAACTATTGGAAACAAATGGTTTTTTTATATATACTTACTATGCAGGCCAAAGGGGCCCCACGGACT CACCCAGGGACATAATCTGGCTCCCAGGTGGCTGCTTTTCCTCACATCTGTTCATCTTCTCAATCTCAAG TTATCTGGCCGCATCTCTTCCCCCTTCAAGGTCAAGTCCTTGGTGCCTGGCCTCAAAGAGGGCTCAGCCT GCACTAGAGCAGGTCTACATGGCTTCTGAGAGCTGGGCACTGTGCCAACTTCCGAGCCATCACCACCAGA GTAGAGGGGTTCACACTGGAGTAGATCCCACCTAGCAGCCACCACGTGGAACAGGGGTCCTGTGAAGAGA GTGGGTCCCACATCAGGTTGCACCATGACAACTTCCTGAGCCTCCTCGGACAGCCCAGGTTCTGGACTAG AAGACTGGTCTGGCAATAAATCTTTTTAACTTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI |
ACCN NM_010299
Insert Size 582 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC004651, AAH04651
RefSeq Size 2024 bp
RefSeq ORF 582 bp
Locus ID 14667
UniProt ID Q60648
Cytogenetics 11 32.13 cM
Summary Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity.UniProtKB/Swiss-Prot Function
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"NM_010299" in other vectors (4)
SKU Description Size Price
MG201862 Gm2a (tGFP-tagged) - Mouse GM2 ganglioside activator protein (Gm2a) 10 ug
$489.00 $500.00
MR201862 Gm2a (Myc-DDK-tagged) - Mouse GM2 ganglioside activator protein (Gm2a) 10 ug
$289.00 $300.00
MR201862L3 Lenti ORF clone of Gm2a (Myc-DDK-tagged) - Mouse GM2 ganglioside activator protein (Gm2a) 10 ug
$600.00
MR201862L4 Lenti ORF clone of Gm2a (mGFP-tagged) - Mouse GM2 ganglioside activator protein (Gm2a) 10 ug
$600.00

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