Casp4 (NM_007609) Mouse Untagged Clone
SKU
MC205003
Casp4 (untagged) - Mouse caspase 4, apoptosis-related cysteine peptidase (Casp4), (10ug)
$457.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Casp4 |
| Synonyms | Cas; CASP-4; CASP-11; Casp11; Caspa; Caspl; ich-; ich-3 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SfiI-SfiI | |
| ACCN | NM_007609 |
| Insert Size | 1122 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC061255, AAH61255 |
| RefSeq Size | 1378 bp |
| RefSeq ORF | 1122 bp |
| Locus ID | 12363 |
| UniProt ID | P70343 |
| Cytogenetics | 9 2.46 cM |
| Summary | This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. provided by RefSeq, Apr 2015 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_007609" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG205770 | Casp4 (tGFP-tagged) - Mouse caspase 4, apoptosis-related cysteine peptidase (Casp4) | 10 ug |
$886.00
|
|
| MR205770 | Casp4 (Myc-DDK-tagged) - Mouse caspase 4, apoptosis-related cysteine peptidase (Casp4) | 10 ug |
$686.00
|
|
| MR205770L3 | Lenti ORF clone of Casp4 (Myc-DDK-tagged) - Mouse caspase 4, apoptosis-related cysteine peptidase (Casp4) | 10 ug |
$986.00
|
|
| MR205770L4 | Lenti ORF clone of Casp4 (mGFP-tagged) - Mouse caspase 4, apoptosis-related cysteine peptidase (Casp4) | 10 ug |
$986.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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