Ubash3b (NM_176860) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Ubash3b |
| Synonyms | 2810457I06Rik; BB125008; p70; TULA-2 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_176860 |
| Insert Size | 1917 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC053436, AAH53436 |
| RefSeq Size | 3274 bp |
| RefSeq ORF | 1917 bp |
| Locus ID | 72828 |
| UniProt ID | Q8BGG7 |
| Cytogenetics | 9 A5.1 |
| Summary | Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.UniProtKB/Swiss-Prot Function Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_176860" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG209668 | Ubash3b (tGFP-tagged) - Mouse RIKEN cDNA 2810457I06 gene (2810457I06Rik) | 10 ug |
$795.00
|
|
| MR209668 | Ubash3b (Myc-DDK-tagged) - Mouse ubiquitin associated and SH3 domain containing, B (Ubash3b) | 10 ug |
$289.00
$595.00
|
|
| MR209668L3 | Lenti ORF clone of Ubash3b (Myc-DDK-tagged) - Mouse ubiquitin associated and SH3 domain containing, B (Ubash3b) | 10 ug |
$895.00
|
|
| MR209668L4 | Lenti ORF clone of Ubash3b (mGFP-tagged) - Mouse ubiquitin associated and SH3 domain containing, B (Ubash3b) | 10 ug |
$895.00
|
|
Citations
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