Prss12 (NM_008939) Mouse Untagged Clone
SKU
MC204559
Prss12 (untagged) - Mouse protease, serine, 12 neurotrypsin (motopsin) (Prss12), (10ug)
$698.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Prss12 |
| Synonyms | Bssp-3; motopsin |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_008939 |
| Insert Size | 2286 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC031429, AAH31429 |
| RefSeq Size | 2525 bp |
| RefSeq ORF | 2286 bp |
| Locus ID | 19142 |
| UniProt ID | O08762 |
| Cytogenetics | 3 G1 |
| Summary | Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_008939" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG210519 | Prss12 (tGFP-tagged) - Mouse protease, serine, 12 neurotrypsin (motopsin) (Prss12) | 10 ug |
$897.00
|
|
| MR210519 | Prss12 (Myc-DDK-tagged) - Mouse protease, serine, 12 neurotrypsin (motopsin) (Prss12) | 10 ug |
$589.00
$697.00
|
|
| MR210519L3 | Lenti ORF clone of Prss12 (Myc-DDK-tagged) - Mouse protease, serine, 12 neurotrypsin (motopsin) (Prss12) | 10 ug |
$997.00
|
|
| MR210519L4 | Lenti ORF clone of Prss12 (mGFP-tagged) - Mouse protease, serine, 12 neurotrypsin (motopsin) (Prss12) | 10 ug |
$997.00
|
|
Citations
Presenilins Regulate Neurotrypsin Gene Expression and Neurotrypsin-Dependent Agrin Cleavage via CREB Modulation
Almenar-Queralt, Kim, Benner et al
J. Biol. Chem. (2013)
Almenar-Queralt, Kim, Benner et al
J. Biol. Chem. (2013)
AI Summary: OriGene contributed to this study by providing the mouse cDNA clone containing CMV-Neurotrypsin, which was used to investigate the regulation and function of Neurotrypsin in the context of presenilin-mediated gene expression.
Snippet: The anti- H3K9me3 (ab8898) and anti-H3K27ac (ab4729) were purchased from Abcam. The mouse cDNA clone containing CMV-Neurotrypsin was purchased from Origene. The siRNA for mouse Mecp2 and mouse Neurotrypsin were purchased from Dharmacon.
Showing 1-1 of 1 papers.
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