Rlim (NM_011276) Mouse Untagged Clone
$559.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Rlim |
| Synonyms | AL022832; AW743871; Ha1r; Rlim1; Rnf12 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_011276 |
| Insert Size | 1803 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC012960, AAH12960 |
| RefSeq Size | 1974 bp |
| RefSeq ORF | 1803 bp |
| Locus ID | 19820 |
| UniProt ID | Q9WTV7 |
| Cytogenetics | X D |
| Summary | E3 ubiquitin-protein ligase that acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1. By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_011276" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG209309 | Rlim (tGFP-tagged) - Mouse ring finger protein 12 (Rnf12) | 10 ug |
$759.00
|
|
| MR209309 | Rlim (Myc-DDK-tagged) - Mouse ring finger protein, LIM domain interacting (Rlim) | 10 ug |
$289.00
$559.00
|
|
| MR209309L3 | Lenti ORF clone of Rlim (Myc-DDK-tagged) - Mouse ring finger protein, LIM domain interacting (Rlim) | 10 ug |
$859.00
|
|
| MR209309L4 | Lenti ORF clone of Rlim (mGFP-tagged) - Mouse ring finger protein, LIM domain interacting (Rlim) | 10 ug |
$859.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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