Abcb8 (NM_029020) Mouse Untagged Clone

SKU MC203835

Abcb8 (untagged) - Mouse ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8), nuclear gene encoding mitochondrial protein, (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Abcb8
• Synonyms: 4833412N02Rik; AA409895
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC015301; AAGGATGGGAGCATAGAGATTGTCTGGAACAACTCTAGAGAAAGGGCTCAAGGTCAGAAGCGCCAGGACG TCCTCTAATGTGAGAATGAACGTCGCACAACCTCTGACCCGCACCTGACTTCAGGCCACTGAGCAAATAG CTAGAGCTGCTTCTGCTCGGTCCCGCCTACAGCCAACATTTTATCCAATCACAGCTTGCAGCAAGACTGA TGTGTCTTTTCTCCAATCATCGCTGAGAATGGGAAGGGGTTGTCGGGATGGGGCCATAGCGAACATGGAA CCCTCGGTAGGATAAGTGTGAGATTGCCGTTGCTGGCTGCCCCTATCTTATTGCCTCAACATGTTGGTGC ACTTATTTCGGTTCGGAATCCGGGGTGGCCCAGTTCCAGGATGGTCGCTACAATCCCTGCGCTTCCAGAC GTTCTCTGCCGCCAGGTCCTCAGATGACCGGCTCAGCTCACACCTCCTGCGGACTGTAGCCCAGCTCCGT GTACAGCTCCGGGCTCACCTCCCTCGAGCCCCACCAGCTTCCCACTGGAGCCCCTCTGCCTGGTGTTGGG TTGGGGGGACCTTGGTGGTCCCTGCAGTCCTGTGGCAGCATCCACGCCTCTGCCTTATAGCACTATGTGA GGCCAAAGAGTCCCCTCCTGCCCAGCCCACACGTGCCCCAGAGCTGCGCTTTAATTGGAAGCTCTTCTGG CATTTCCTTCACCCCCACCTGCTGGCCTTGGGGGCAGCCATTGTGCTGGCCTTAGGTGCGGCACTAGTGA ATGTGCAGATCCCCTTGCTCCTGGGCCAGCTGGTGGAGATTGTCGCCAAGTACACGAGGGACCACATGGG GAGTTTCGTGTCTGAGTCCCGTAAGCTCAGCGTCCAGCTGCTCCTACTGTACGGTGTTCAGGGACTGCTG ACCTTTGGATACCTAGTGCTGCTGTCCCACATTGGTGAGCGCATGGCCATGGACATGCGGAAAGCCCTTT TCAGCTCCCTGCTCCGGCAAGACATTGCTTTCTTTGATGCCAAAAAGACAGGGCAGCTAGTGAGTCGCTT GACTACTGATGTGCAAGAATTCAAGTCATCCTTCAAGCTTGTCATCTCCCAGGGACTGCGCAGCTGCACC CAGGTGATTGGTAGCCTGGTGTCCCTGTCTATGCTGTCCCCTCGCCTTACCCTGATGCTGGCTGTCGTCA CACCCGCCCTCATGGGAGTGGGCACCCTGATGGGCTCAGGCCTCCGAAAGCTGTCTCGCCAGTGTCAGGA GCAGATTGCCAGGGCAACAGGTGTAGCAGATGAGGCCCTTGGCAATGTTCGGACTGTGCGGGCCTTCGCG ATGGAGAAGAGGGAGGAGGAACGCTATCAAGCAGAACTGGAGTCATGCTGCTGTAAAGCAGAAGAACTGG GCAGGGGCATCGCCTTGTTCCAAGGGCTCTCCAACATCGCTTTCAACTGTATGGTCTTGGGCACCCTGTT CATTGGGGGCTCCCTTGTGGCTGGACAGCAGCTGAAAGGGGGAGACCTCATGTCCTTCCTGGTGGCTTCC CAGACAGTACAGAGGTCTATGGCCAGCCTCTCTGTCCTGTTTGGTCAGGTGGTACGTGGGCTGAGTGCGG GAGCCCGAGTCTTCGAATACATGGCCCTGAGCCCTGTCATCCCATTGACCGGGGGCTACTGCATCCCCAA CAAGGACATTCGTGGTTCCATCACCTTCCAAAATGTCACCTTCAGCTACCCCTGCAGACCTGGCTTCAAT GTGCTCAAGGACTTCACCCTGAAGCTGCCCTCTGGCAAGATTGTGGCTCTTGTGGGCCAGTCTGGGGGAG GAAAGACCACAGTTGCCTCCTTGCTGGAACGCTTCTATGACCCTGAAGCTGGCTCGGTGACGTTGGATGG GCATGACCTGCGAACTCTCAACCCCTCCTGGCTCCGGGGCCAGGTCATAGGTTTCATCAGCCAGGAGCCA GTCCTGTTTGCAACAACCATCATGGAGAATATCCGATTTGGGAAGCTGGATGCTTCCGATGAAGAGGTGT ACACAGCTGCACGAGAAGCCAATGCCCACGAGTTCATCAGCAGCTTCCCCGATGGCTACAGCACTGTGGT TGGTGAGCGGGGCACAACCTTGTCTGGTGGCCAGAAGCAGCGCCTAGCCATCGCACGTGCCCTCATCAAG CAGCCCACAGTGCTGATCCTGGACGAGGCCACCAGTGCGCTAGATGCAGAATCCGAGAGGGTGGTACAGG AGGCCCTGGACCGGGCCAGTGCTGGCCGCACCGTGTTGGTCATTGCCCACCGGCTTAGTACTGTCCGTGC AGCCCACTCCATCATTGTCATGGCCAATGGCCAAGTCTGTGAGGCTGGGACCCACGAAGAACTCCTTAAA AAAGGCGGGCTCTATTCAGAGCTTATCCGGAGACAAACCCTGGACGCCTCACTGACCTCAACCCCTCCTG CAGAGAAGCCTGAAGACCCCAAAAGCTGCCAGTCCAAAGCCTGAGAGGCCCCCTGGGGTCAGGTCACTGC AAGACATCAGTCTGAGGCTGGAGCTCTGCTGGGGACAGAGCCCTTGGAAGGCCAGTGTGCTGGAGTGTGG CCTGCACTACTGCCCCCTTAAAGGAGCTGGGCTCAACAGCTGGGGTGGGAAATGGCTCTCCGCCCACCTG CTCTGACCATCCTGACTCAGCTCTGTGGTCACGGGATGTACACAGTGAGACAGAGTCCCTGGACACCTCT GCTTGACCCTCTCAGGCTGGCCTGGTTCTGCCCAACACTCAGTTGTTTGGGCCCTCACTCCAGGAGACTG GCCAGGCCTGGTAGAATGGGTTGTAATCCCAGCACTTGGGAGACAGAAGTGGGAGGGTCAAGAGTTCAAG GCCATCCTGGGCTAAATAGTGAGACCCTCTCTCAACAAAAAGAAAAACCTAAATAAAGAGGAAAAATTTT CAAAGAGAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_029020
• Insert Size: 2154 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC015301, AAH15301
• RefSeq Size: 2962 bp
• RefSeq ORF: 2154 bp
• Locus ID: 74610
• UniProt ID: Q9CXJ4
• Cytogenetics: 5 A3
• Summary: ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (By similarity). Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (By similarity). Plays a role in mitochondrial iron transport (PubMed:22375032). Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (PubMed:22375032).[UniProtKB/Swiss-Prot Function]