Rad17 (NM_011233) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Rad17 |
| Synonyms | MmRad24 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_011233 |
| Insert Size | 2067 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC066855, AAH66855 |
| RefSeq Size | 2853 bp |
| RefSeq ORF | 2067 bp |
| Locus ID | 19356 |
| UniProt ID | Q6NXW6 |
| Cytogenetics | 13 D1 |
| Summary | Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination (By similarity). Essential for embryonic development. May be involved in homologous recombination.UniProtKB/Swiss-Prot Function Transcript Variant: This variant (1) encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_011233" in other vectors (1)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG210047 | Rad17 (tGFP-tagged) - Mouse RAD17 homolog (S. pombe) (Rad17), transcript variant 1 | 10 ug |
$830.00
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Citations
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