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Edem2 (NM_145537) Mouse Untagged Clone

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SKU
MC200261
Edem2 (untagged) - Mouse ER degradation enhancer, mannosidase alpha-like 2 (Edem2), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $538.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Edem2
Synonyms 9530090G24Rik; AI327354
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC008268 sequence for NM_145537
GTGGCGGTGGCTGCAGCTGCTGCGGCGGCACTGACAGGACACGAGCTCTATGCCTTTCCGGCTACTCATC CCGCTCGGCCTCGTGTGCGTGCTGCTACCCCTGCACCATGGTGCGCCAGGCCCCGACGGCACCGCGCCCG ACCCCGCCCACTACAGGGAGCGAGTCAAGGCCATGTTCTACCACGCCTACGACAGTTACCTGGAAAATGC CTTTCCCTACGATGAGCTGAGACCTCTCACCTGTGATGGGCACGACACCTGGGGCAGTTTTTCTCTGACG CTAATTGATGCCCTGGACACCTTGCTGATTTTGGGGAATACCTCTGAATTCCAAAGAGTAGTGGAGGTTC TTCAGGACAATGTGGACTTTGATATCGACGTGAACGCCTCTGTGTTCGAAACCAACATCCGAGTGGTAGG AGGACTCCTTTCTGCTCATCTCTTGTCAAAGAAGGCCGGTGTGGAGGTGGAAGCCGGGTGGCCTTGTTCT GGGCCTCTCCTCAGGATGGCGGAGGAAGCAGCCCGGAAACTCCTCCCAGCATTTCAGACCCCCACGGGCA TGCCCTATGGAACTGTGAACCTGCTTCATGGCGTGAACCCTGGAGAGACCCCTGTTACCTGTACAGCAGG GATTGGGACCTTCATTGTGGAATTTGCTACCCTGAGCAGCCTCACCGGTGACCCTGTGTTTGAAGATGTG GCCAGAGTGGCCCTGATGCGTCTCTGGGAGAGCCGGTCAGATATCGGGCTGGTTGGCAATCACATCGATG TGCTCACTGGCAAGTGGGTGGCCCAGGATGCAGGCATCGGGGCTGGTGTGGATTCCTATTTTGAGTACCT GGTAAAAGGAGCCATCCTTCTTCAGGATAAGAAACTCATGGCCATGTTCCTAGAGTACAACAAAGCCATC CGGAATTACACGCACTTCGATGACTGGTACCTCTGGGTGCAGATGTACAAGGGGACCGTGTCAATGCCTG TCTTCCAGTCCTTGGAGGCCTACTGGCCTGGCCTTCAGAGCCTTATTGGAGACATTGACAATGCCATGAG GACCTTTCTCAACTACTACACTGTATGGAAGCAGTTTGGGGGGCTGCCAGAATTCTACAACATTCCTCAG GGATACACAGTGGAGAAGCGAGAAGGCTACCCACTCCGACCGGAGCTCATCGAGAGCGCAATGTACCTCT ACCGCGCCACTGGGGATCCCACTCTCTTAGAACTTGGGAGAGACGCTGTGGAATCCATTGAGAAAATCAG CAAGGTGGAGTGTGGATTTGCCACGATCAAGGACCTCCGGGACCACAAGCTTGACAACCGCATGGAGTCT TTCTTCCTGGCTGAAACTGTGAAATACCTCTATCTTCTGTTCCACCCAAACAACTTCATCCACAACAATG GCTCCACCTTTGACTCTGTGATGACTCCCCATGGGGAGTGCATCCTAGGAGCCGGGGGCTACATCTTCAA CACGGAGGCTCACCCCATTGACCCTGCTGCCTTGCACTGCTGCCGGAGGCTCAAGGAGGAGCAGTGGGAA GTGGAGGACTTGATAAAGGAGTTCTACTCCCTCAAACAGAGCAGGCCAAAGAGAGCTCAGAGGAAGACAG TGAGGTCGGGGCCCTGGGAGCCCCAGTCAGGGCCAGCCACACTCTTCTCACCTGCAAACCAGCCCAGGGA GAAGCAGCCTGCCCGGCAGCGAACCCCGCTTCTCAGCTGCCCCAGCCAGCCCTTCACCTCTAAGCTGGCA TTGCTAGGCCAGGTTTTCCTAGACTCCTCATAGCCACTGGATAATTTTCTAATTTTTATTTTTTTGAGAC TAAGCTCTAATAATAAATCTGCTTTTGGCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI |
ACCN NM_145537
Insert Size 1734 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC008268, AAH08268
RefSeq Size 1926 bp
RefSeq ORF 1734 bp
Locus ID 108687
UniProt ID Q8BJT9
Cytogenetics 2 H1
Summary Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner (PubMed:15579471, PubMed:25655076). May initiate ERAD by promoting the first mannose trimming step of ERAD substrates, from Man9GlcNAc2 to Man8GlcNAc2 (By similarity). Seems to recognize and bind to exposed hydrophobic regions in target proteins (PubMed:25655076).UniProtKB/Swiss-Prot Function
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"NM_145537" in other vectors (4)
SKU Description Size Price
MG209050 Edem2 (tGFP-tagged) - Mouse ER degradation enhancer, mannosidase alpha-like 2 (Edem2) 10 ug
$738.00
MR209050 Edem2 (Myc-DDK-tagged) - Mouse ER degradation enhancer, mannosidase alpha-like 2 (Edem2) 10 ug
$289.00 $538.00
MR209050L3 Lenti ORF clone of Edem2 (Myc-DDK-tagged) - Mouse ER degradation enhancer, mannosidase alpha-like 2 (Edem2) 10 ug
$838.00
MR209050L4 Lenti ORF clone of Edem2 (mGFP-tagged) - Mouse ER degradation enhancer, mannosidase alpha-like 2 (Edem2) 10 ug
$838.00

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