Human CD70 ELISA Kit 1 kit
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Format | 8x12 divisible strips |
| Assay Type | microplate ELISA |
| Assay Length | 3.5 hours incubations; 0.5 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 7.8-500ng/mL |
| Sample Type | Human serum, plasma and other biological fluids. |
| Sample Volume | 100µl |
| Specificity | This kit is used for quantitative detection of CD70 |
| Sensitivity | 1.82pg/mL |
| Reactivity | Human |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Interference | No significant interference observed with available related molecules. |
| Components |
|
| Background | CD70 (Cluster of Differentiation 70) also known as a ligand for CD27, is a protein that in humans is encoded by CD70 gene. In physiological condition the expression of CD70 on immune cells is transient and tightly controlled. It is primarily expressed on highly activated T cells and B cells, as well as on NK cells and mature dendritic cells. CD70 Antigen is overexpressed in several types of cancer including Hodgkin's lymphoma and non-Hodgkin's lymphoma, and leukemias. This overexpression of CD70 in cancer cells has been shown to promote cell proliferation and survival, and to inhibit apoptosis, leading to the development and progression of cancer. High CD70 expression is often associated with aggressive disease and poor prognosis. Soluble CD70 can be detected in blood and may reflect tumor burden or immune activation. In addition, changes in soluble or tissue CD70 may correlate with treatment response or progression, which makes it a disease monitoring biomarker. |
| Gene Symbol | CD70 |
| Locus ID | 970 |
| Standard Curve |
|
| Shipping | Blue Ice |
Reviews
Documents
| Datasheet | |
| Manual | |
| SDS | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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