Human Smith antigen (Sm) IgG ELISA kit
$250.00
3 Weeks*
| Product Data | |
| Species | Human |
|---|---|
| Format | 8x12 divisible strips |
| Assay Type | Solid Phase Sandwich ELISA |
| Assay Length | 3 hours |
| Signal | Colorimetric |
| Sample Type | Serum |
| Sample Volume | 10 µl/well |
| Specificity | This kit is used for quantitative detection human Smith antigen (Sm) IgG |
| Reactivity | Human |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Interference | No significant interference observed with available related molecules. |
| Components |
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| Background | Systemic autoimmune disease is characterized by the presence of circulating auto-antibodies directed to a wide variety of cellular antigens. Systemic lupus erythematosis (SLE), commonly referred to as Lupus is the best known of these diseases. Other possible connective tissue diseases include mixed connective tissue disease (MCTD), Sjogren syndrome, sclerodema, and polymyositis/dermatomyositis. The majority can be diagnosed by clinical presentation and their antibody profiles to the various antigens involved, which include dsDNA, SM, RNP, Ro, La Scl- 70, Jo1 and Histones. Therefore, immunoassays for autoantibodies are useful for diagnostic and prognostic evaluations of autoimmune disease. The SM or Smith antigen is composed of nuclear RNA and several polypeptides. Antibodies to SM are present in approximately 30% of patients with SLE (systemic lupus erythematosis). SM is a very specific marker for SLE. SM antibodies are very rare in other autoimmune diseases and normals. |
| Shipping | Blue Ice |
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| Datasheet | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.