Human C-Reactive Protein ELISA kit

SKU
EA100881
Human C-Reactive Protein ELISA kit
  $290.00
3 Weeks*
Specifications
Specifications
Product Data
Species Human
Format 8x12 divisible strips
Assay Type Solid Phase Sandwich ELISA
Assay Length 3 hours
Signal Colorimetric
Curve Range 0.005-0.1 mg/l
Sample Type Serum
Sample Volume 5 µl/well
Specificity This kit is used for quantitative detection human C-Reactive Protein
Sensitivity 0.005 mg/l
Reactivity Human
Cross Reactivity There is no detectable cross-reactivity with other relevant proteins.
Interference No significant interference observed with available related molecules.
Components
  • 1. Microwells coated with CRP MAb: 12x8x1
  • 2. CRP Standard: 6 vials ( ready to use): 0.25ml
  • 3. CRP Enzyme Conjugate: 1 bottle (ready to use): 12 ml
  • 4. TMB Substrate: 1 bottle (ready to use): 12ml
  • 5. Stop Solution: 1 bottle (ready to use): 12ml
  • 6. Sample Diluent: 2 bottles (2x 25 ml): 50 ml
  • 7. 20X Wash concentrate: 1 bottle: 25ml
Background C-Reactive protein (CRP) is an alpha globulin with a molecular mass of approximately 110,000 to 140,000 daltons, and is composed of five identical subunits, which are noncovalently assembled as a cyclic pentamer. CRP is synthesized in the liver and is normally present as a trace constituent of serum or plasma at levels less than 0.3 mg/dl. CRP is one of the acute-phase proteins, the serum or plasma levels of which rise during general, nonspecific response to a wide variety of diseases. Although the detection of elevated levels of CRP in the serum is not specific for any particular disease, it is a useful indicator of inflammatory processes. Additionally, measurement of CRP by high-sensitivity CRP assays may add to the predictive value of other cardiac markers (myoglobin, creatine-kinase-MB, troponin I and T), which are used to assess the risk of cardiovascular and peripheral vascular disease. Inflammation in the arteries may play a role in heart disease and HS-CRP can determine heart disease risk in those with undetected heart disease and risk of complications for those who have already had a heart event.
Gene Symbol CRP
Locus ID 1401
Shipping Blue Ice
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Documents
Resources

file-alt Citations

A Pilot Interaction Analysis of Gut Microbiota and Peripheral Markers of Aging in Severe Psychiatric Disorders: A Role for Lachnoclostridium?
Manchia, Paribello, Pisanu et al
Int J Mol Sci (2023) 24 (24) DOI: 10.3390/ijms242417618
Cited by 7
AI Summary: OriGene's high-sensitivity C-reactive protein (CRP) ELISA sandwich kits (catalog number EA100881) were used to measure plasma CRP levels, enabling assessment of inflammatory markers in the study's analysis of gut microbiota and aging in severe psychiatric disorders.
Snippet: RP Each relevant aliquot was thawed once, immediately before running the respective ELISA assay. Plasma levels of the C-reactive protein (CRP) were measured with high-sensitivity ELISA sandwich kits (Origene: catalog number EA100881), as described in detail in Ref. [20]. The detection limit of the ELISA kits used was 0.02–3.3 mg/L. 4.5. Statistical Analysis To test for interaction between the t
Showing 1-1 of 1 papers.
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