Mouse DMP-1 ELISA Kit
USD 705.00
3 Weeks*
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Specifications
Product Data | |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse DMP-1 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 156pg/ml-10,000pg/ml |
Sample Type | Cell culture supernates, serum, plasma(heparin, EDTA) and tissue homogenates. |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of mouse DMP-1 |
Sensitivity | <10pg/ml |
Reactivities | Mouse |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Dentin matrix acidic phosphorprotein 1 is a protein that in humans is encoded by the DMP1 gene. It belongs to the small integrin-binding ligand N-linked glycoprotein(SIBLING) family of secreted phosphoproteins. This gene is mapped to 4q22.1. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. In undifferentiated osteoblasts, DMP-1 is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation, the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. |
Gene Symbol | Dmp1 |
Gene ID | 13406 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.