Human Corin ELISA Kit
USD 705.00
3 Weeks*
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Specifications
Product Data | |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human Corin |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 62.5pg/ml-4000pg/ml |
Sample Type | Cell culture supernates, serum, plasma(heparin, EDTA) and tissue homogenates. |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of human Corin |
Sensitivity | <10pg/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Atrial natriuretic peptide-converting enzyme, also called CRN or ATC2, is a protein that in humans is encoded by the CORIN gene. It is mapped to 4p12. This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. It has been found that Corin is the pro-ANP-converting enzyme and that Corin-mediated pro-ANP activation may play a role in regulating blood pressure. What’s more, Corin and ANP are essential for physiologic changes at the maternal-fetal interface. This protein may also function as a pro-brain-type natriuretic peptide convertase. Corin gene mutations which cause Corin to impair activity might be an underlying mechanism in hypertension. |
Gene Symbol | CORIN |
Gene ID | 10699 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.