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Mouse SAP/PTX2 ELISA Kit

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SKU
EA100713
Mouse SAP/PTX2 ELISA Kit
  $755.00
3 Weeks*
Specifications
Specifications
Product Data
Species Mouse
Assay Type Sandwich ELISA kit of Quantitative Detection for Mouse SAP/PTX2
Assay Length 3.5 hours incubations; 1 hour washing and analyzing samples
Signal Colorimetric
Curve Range 1.56ng/ml-100ng/ml
Sample Type Cell culture supernates, serum and plasma(heparin, EDTA).
Sample Volume 100 ul
Specificity This kit is used for quantitative detection of mouse SAP
Sensitivity <50pg/ml
Reactivity Mouse
Cross Reactivity There is no detectable cross-reactivity with other relevant proteins.
Interference No significant interference observed with available related molecules.
Components
  • 96-well plate precoated with anti- mouse SAP antibody 1
  • Lyophilized recombinant mouse SAP standard 100ng/tubex2
  • Biotinylated anti- mouse SAP antibody 130ul(dilution 1:100)
  • Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100)
  • Sample diluent buffer 30 ml
  • Antibody diluent buffer 12ml
  • ABC diluent buffer 12ml
  • TMB color developing agent 10ml
  • TMB stop solution 10ml
Background Amyloid P component, serum(SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component(AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened beta-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Gene Symbol Apcs
Locus ID 20219
Shipping Blue Ice
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Documents
Resources

file-alt Citations

Immunosuppressive Potential of Activated Human Amniotic Cells in an Experimental Murine Model of Skin Allo- and Xenotransplantation
Kolanko, Grajoszek, Czekaj
Front Med (Lausanne) (2021) 8, 715590 DOI: 10.3389/fmed.2021.715590
Cited by 4
AI Summary: In this study, OriGene’s Human IL-1 beta (Cat# Z02944-1) and Human IFN gamma (Cat# Z02950-1) recombinant proteins were used to activate human amniotic cells ex vivo, enabling the researchers to evaluate the enhanced immunosuppressive effects of these cells in a murine model of skin allo- and xenotransplantation.
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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