Mouse TGF-beta 3 ELISA Kit

USD 500.00


Availability*
3 Weeks

Size
    • 1 x 96 wells

Product images

Specifications

Product Data
Description Mouse TGF-beta 3 ELISA Kit
Type Sandwich ELISA kit of Quantitative Detection for Mouse TGF-beta 3
Size 1 x 96 wells
Assay Type Sandwich ELISA kit of Quantitative Detection for Mouse TGF-beta 3
Assay Length 3.5 hours incubations; 1 hour washing and analyzing samples
Signal Colorimetric
Curve Range 31.2pg/ml-2000pg/ml
Sample Type Cell culture supernates, serum, plasma(EDTA) and urine.
Sample Volume 100 ul
Specificity This kit is used for quantitative detection of activated mouse TGF-beta 3
Sensitivity <10pg/ml
Reactivity Mouse
Cross Reactivity There is no detectable cross-reactivity with other relevant proteins.
Interference No significant interference observed with available related molecules.
Components
  • 96-well plate precoated with anti- mouse TGF-beta 3 antibody 1
  • Lyophilized recombinant mouse TGF-beta 3 standard 10ng/tubex2
  • Biotinylated anti- mouse TGF-beta 3 antibody 130ul(dilution 1:100)
  • Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100)
  • Sample diluent buffer 30 ml
  • Antibody diluent buffer 12ml
  • ABC diluent buffer 12ml
  • TMB color developing agent 10ml
  • TMB stop solution 10ml
Background Transforming growth factor beta 3(TGF-beta 3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily. TGF-beta 3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix(ECM) formation during the process of palate development. Without TGF-beta 3, mammals develop a deformity known as acleft palate. This is caused by failure of epithelial cells in both sides of the developing palate to fuse. TGF-beta 3 also plays an essential role in controlling the development of lungs in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. TGF-beta 3 activated Lef1 in the absence of beta-catenin(CTNNB1) via nuclear phospho-Smad2 and Smad4.
Gene Symbol Tgfb3
Gene ID 21809

Citations (1)

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68 Mouse Clones