Human CD23/FCER2 ELISA Kit
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Assay Type | Sandwich ELISA kit of Quantitative Detection for Human CD23/FCER2 |
| Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 31.2pg/ml-2000pg/ml |
| Sample Type | Cell culture supernates, serum, plasma(heparin, EDTA) and urine. |
| Sample Volume | 100 ul |
| Specificity | This kit is used for quantitative detection of human CD23 |
| Sensitivity | <10pg/ml |
| Reactivity | Human |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Interference | No significant interference observed with available related molecules. |
| Components |
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| Background | CD23, also known as Fc epsilon RII, or FceRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23(FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor. |
| Gene Symbol | FCER2 |
| Locus ID | 2208 |
| Shipping | Blue Ice |
Reviews
Documents
| Datasheet | |
| SDS | |
Citations
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