Mouse CXCL4/PF4 ELISA Kit
$755.00
3 Weeks*
| Product Data | |
| Species | Mouse |
|---|---|
| Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse CXCL4/PF4 |
| Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 15.6pg/ml-1000pg/ml |
| Sample Type | Cell culture supernates, serum and plasma(heparin, EDTA). |
| Sample Volume | 100 ul |
| Specificity | This kit is used for quantitative detection of mouse CXCL4 |
| Sensitivity | <1pg/ml |
| Reactivity | Mouse |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Interference | No significant interference observed with available related molecules. |
| Components |
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| Background | Platelet factor 4(PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine(C-X-C motif) ligand 4(CXCL4). The PF4 gene was localized on map to 4q12-q13. Chemokines play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. |
| Gene Symbol | Pf4 |
| Locus ID | 56744 |
| Shipping | Blue Ice |
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| Datasheet | |
| SDS | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.