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Mouse VEGFR2/KDR ELISA Kit

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SKU
EA100405
Mouse VEGFR2/KDR ELISA Kit
  $755.00
3 Weeks*
Specifications
Specifications
Product Data
Species Mouse
Assay Type Sandwich ELISA kit of Quantitative Detection for Mouse VEGFR2/KDR
Assay Length 3.5 hours incubations; 1 hour washing and analyzing samples
Signal Colorimetric
Curve Range 62.5pg/ml-4000pg/ml
Sample Type Cell culture supernates and serum.
Sample Volume 100 ul
Specificity This kit is used for quantitative detection of mouse VEGFR2
Sensitivity <2pg/ml
Reactivity Mouse
Cross Reactivity There is no detectable cross-reactivity with other relevant proteins.
Interference No significant interference observed with available related molecules.
Components
  • 96-well plate precoated with anti- mouse VEGFR2 antibody 1
  • Lyophilized recombinant mouse VEGFR2 standard 10ng/tubex2
  • Biotinylated anti- mouse VEGFR2 antibody 130ul(dilution 1:100)
  • Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100)
  • Sample diluent buffer 30 ml
  • Antibody diluent buffer 12ml
  • ABC diluent buffer 12ml
  • TMB color developing agent 10ml
  • TMB stop solution 10ml
Background Vascular endothelial growth factor receptor 2(VEGFR-2) is a VEGF receptor. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It is mapped to 4q12. This gene encodes one of the two receptors of the VEGF. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. VEGF receptor 2 and the adherens junction act as shear-stress cotransducers, mediating the transduction of shear-stress signals into vascular endothelial cells. In addition to those, VEGFR-2 is also a positive functional marker defining stem cells and distinguishing them from progenitors.
Gene Symbol Kdr
Locus ID 16542
Shipping Blue Ice
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Documents
Resources

file-alt Citations

Anti-angiogenic effect of a chemically sulfated polysaccharide from Phellinus ribis by inhibiting VEGF/VEGFR pathway
Ding, Jia, Cui et al
Int. J. Biol. Macromol. (2020) 154, 72-81 DOI: 10.1016/j.ijbiomac.2020.03.068
Cited by 34
AI Summary: OriGene’s Mouse VEGF ELISA Kit and Mouse VEGFR-2/KDR ELISA were used in this study to quantitatively measure VEGF and VEGFR-2 protein levels, helping to demonstrate the anti-angiogenic effects of PRP-S16 by assessing its impact on key angiogenesis markers.
Snippet: Fluorescently labeled monoclonal antibodies CD31 (bs-20319R), VEGF (bs-1313R) and VEGFR-2 (bs-10412R) were from Bioss Antibodies (Beijing, China). Mouse VEGF Elisa Kit, Mouse VEGFR-2/KDR ELISA were from OriGene Technologies (USA)
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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