Mouse VCAM-1 ELISA Kit
$755.00
3 Weeks*
| Product Data | |
| Species | Mouse |
|---|---|
| Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse VCAM-1 |
| Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 156pg/ml-10,000pg/ml |
| Sample Type | Cell culture supernates, serum and plasma(heparin, EDTA). |
| Sample Volume | 100 ul |
| Specificity | This kit is used for quantitative detection of mouse VCAM-1 |
| Sensitivity | <5pg/ml |
| Reactivity | Mouse |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Interference | No significant interference observed with available related molecules. |
| Components |
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| Background | Vascular cell adhesion molecule 1(VCAM-1) is a cell surface glycoprotein adhesive for certain blood leukocytes and tumor cells, which is expressed by activated endothelium in a variety of pathologic conditions including atherosclerosis.Increased expression of VCAM1 is associated with a variety of chronic inflammatory conditions, making its expression and function a target for therapeutic intervention.Integrin alpha4beta1(VLA-4) and VCAM-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization.The VCAM1 gene is assigned to the 1p31-32 region of chromosome 1 based on the analysis of human-mouse hybrid cell lines and in situ hybridization.The standard product used in this kit is recombinant mouse VCAM-1, a dimeric protein linking with a disulfide bond. It consists of Phe25-Glu698 amino acid sequence of a single chain with the molecular mass of 101.9KDa. As a result of glycosylation, the molecular mass of 120KDa is revealed by SDS-PAGE. |
| Gene Symbol | Vcam1 |
| Locus ID | 22329 |
| Shipping | Blue Ice |
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| Datasheet | |
| SDS | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.