Mouse OPG ELISA Kit

SKU EA100336

Mouse OPG ELISA Kit

Product Data

• Species: Mouse
• Assay Type: Sandwich ELISA kit of Quantitative Detection for Mouse OPG
• Assay Length: 3.5 hours incubations; 1 hour washing and analyzing samples
• Signal: Colorimetric
• Curve Range: 93.7pg/ml-6000pg/ml
• Sample Type: Cell culture supernates, serum and plasma(EDTA).
• Sample Volume: 100 ul
• Specificity: This kit is used for quantitative detection of mouse OPG
• Sensitivity: <5pg/ml
• Reactivity: Mouse
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Interference: No significant interference observed with available related molecules.
• Components:
  • 96-well plate precoated with anti- mouse OPG antibody 1
  • Lyophilized recombinant mouse OPG standard 10ng/tubex2
  • Biotinylated anti- mouse OPG antibody 130ul(dilution 1:100)
  • Avidin-Biotin-Peroxidase Complex(ABC) 130ul(dilution 1:100)
  • Sample diluent buffer 30ml
  • Antibody diluent buffer 12ml
  • ABC diluent buffer 12ml
  • TMB color developing agent 10ml
  • TMB stop solution 10ml
• Background: Osteoprotegerin(OPG) is identical to osteoclastogenesis inhibitory factor(OCIF), a soluble member of the tumor-necrosis factor receptor family that inhibits osteoclastogenesis. OPG is considered to play an important role in the regulation of bone resorption by modifying osteoclast differentiation. Osteoprotegerin is an independent risk factor for the progression of atherosclerosis and onset of cardiovascular disease. It can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity. OPG system may play a critical role in the development of osteolytic bone disease in multiple myeloma and that targeting this system may have therapeutic potential. OPG also plays a role in the vascular system.
• Gene Symbol: Tnfrsf11b
• Locus ID: 18383
• Shipping: Blue Ice