Bile Acid Receptor (NR1H4) Mouse Monoclonal Antibody [Clone ID: OTI4F12]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI4F12 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21-297 of human NR1H4 (NP_005114) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | nuclear receptor subfamily 1 group H member 4 |
| Database Link | |
| Background | This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Aug 2011 |
| Synonyms | BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 |
| Note | WB application: Only overexpression results are guaranteed, not endogenous |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI4F12" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF809306 | Carrier-free (BSA/glycerol-free) NR1H4 mouse monoclonal antibody,clone OTI4F12 | 100 ug |
$620.00
|
|
| TA809306AM | NR1H4 mouse monoclonal antibody,clone OTI4F12, Biotinylated | 100 ul |
$509.00
|
|
| TA809306BM | NR1H4 mouse monoclonal antibody,clone OTI4F12, HRP conjugated | 100 ul |
$509.00
|
|
| TA809306S | NR1H4 mouse monoclonal antibody,clone OTI4F12 | 30 ul |
$200.00
|
|
Citations
Lycium barbarum L. Balanced intestinal flora with YAP1/FXR activation in drug-induced liver injury
Lu, Gao, Gong et al
International Immunopharmacology (2024) 130, 111762 DOI: 10.1016/j.intimp.2024.111762
Lu, Gao, Gong et al
International Immunopharmacology (2024) 130, 111762 DOI: 10.1016/j.intimp.2024.111762
Cited by 21
AI Summary: OriGene contributed to the study by providing the FXR/NR1H4 mouse monoclonal antibody (TA809306S), which was used to detect FXR protein levels in the investigation of Lycium barbarum L.'s effects on intestinal flora and liver injury.
Snippet: Primary antibodies included the FXR/NR1H4 mouse monoclonal antibody (TA809306S, OriGene, 1:1000), CYP7A1 rabbit polyclonal antibody (DF2612, Affinity Biosciences, 1:1000), CYP27A1 rabbit monoclonal antibody (EPR7529, Abcam, 1:1000), YAP (D8H1X) XP rabbit monoclonal antibody (14074S, CST, 1:1000), and GAPDH rabbit monoclonal antibody (AB0037, Abways, 1:7500). Secondary antib
Showing 1-1 of 1 papers.
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