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NCF4 Mouse Monoclonal Antibody [Clone ID: OTI3E3]

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SKU
TA809196S
NCF4 mouse monoclonal antibody,clone OTI3E3
Size:
30 ul 100 ul
Conjugation:
Unconjugated
  $200.00
In Stock*
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View other "NCF4 or NM_000631" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3E3
Application WB
Recommended Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human NCF4 (NP_000622) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 38.9 kDa
Gene Name neutrophil cytosolic factor 4
Database Link
Background The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. provided by RefSeq, Jul 2008
Synonyms NCF; P40PHOX; SH3PXD4
Reference Data
Protein Categories Immune system diseases, Intracellular Proteins
Protein Pathways Leukocyte transendothelial migration
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Other "OTI3E3" antibodies (4)
SKU Description Size Price
CF809196 Carrier-free (BSA/glycerol-free) NCF4 mouse monoclonal antibody,clone OTI3E3 100 ug
$620.00
TA809196 NCF4 mouse monoclonal antibody,clone OTI3E3 100 ul
$447.00
TA809196AM NCF4 mouse monoclonal antibody,clone OTI3E3, Biotinylated 100 ul
$509.00
TA809196BM NCF4 mouse monoclonal antibody,clone OTI3E3, HRP conjugated 100 ul
$509.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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