CCN2 Mouse Monoclonal Antibody [Clone ID: OTI6D1]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI6D1 |
|---|---|
| Application | IHC, Simple Western, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 Simple Western 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27-349 of human CTGF(NP_001892) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 37.9 kDa |
| Gene Name | connective tissue growth factor |
| Database Link | |
| Background | The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. provided by RefSeq, Nov 2009 |
| Synonyms | CCN2; HCS24; IGFBP8; NOV2 |
| Reference Data | |
| Protein Categories | Growth Factors, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI6D1" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF806802 | Carrier-free (BSA/glycerol-free) CTGF mouse monoclonal antibody, clone OTI6D1 (formerly 6D1) | 100 ug |
$620.00
|
|
| TA806802AM | CTGF mouse monoclonal antibody, clone OTI6D1 (formerly 6D1), Biotinylated | 100 ul |
$509.00
|
|
| TA806802BM | CTGF mouse monoclonal antibody, clone OTI6D1 (formerly 6D1), HRP conjugated | 100 ul |
$509.00
|
|
| TA806802S | CTGF mouse monoclonal antibody, clone OTI6D1 (formerly 6D1) | 30 ul |
$200.00
|
|
Citations
Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells
Rigiracciolo, Santolla, Lappano et al
J. Exp. Clin. Cancer Res. (2019) 38 (1), 58 DOI: 10.1186/s13046-019-1056-8
Rigiracciolo, Santolla, Lappano et al
J. Exp. Clin. Cancer Res. (2019) 38 (1), 58 DOI: 10.1186/s13046-019-1056-8
AI Summary: In this study, the CTGF antibody from OriGene was used to detect CTGF protein levels by western blotting, contributing to the analysis of downstream gene expression changes following GPER and FAK activation in triple-negative breast cancer cells.
Snippet: ERK2 (C-14) (Santa Cruz Biotechnology, DBA, Milan, Italy), p-AKT1/2/3 (Ser 473)-R (Santa Cruz Biotechnology, DBA, Milan, Italy), AKT/1/2/3 (H-136) (Santa Cruz Biotechnology, DBA, Milan, Italy), c-FOS (H-125) (Santa Cruz Biotechnology, DBA, Milan, Italy), EGR1 (C19) (Santa Cruz Biotechnology, DBA, Milan, Italy), CTGF (Origene, DBA, Milan, Italy) and β-actin (C2) (Santa Cruz Biotechnology, DBA, Mila...
Showing 1-1 of 1 papers.
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