LXR alpha (NR1H3) Mouse Monoclonal Antibody [Clone ID: OTI1F5]
Specifications
| Product Data | |
| Clone Name | OTI1F5 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 69-329 of human NR1H3 (NP_005684) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 50.2 kDa |
| Gene Name | nuclear receptor subfamily 1 group H member 3 |
| Database Link | |
| Background | The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2011 |
| Synonyms | LXR-a; LXRA; RLD-1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | PPAR signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI1F5" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF805049 | Carrier-free (BSA/glycerol-free) NR1H3 mouse monoclonal antibody, clone OTI1F5 (formerly 1F5) | 100 ug |
$620.00
|
|
| TA805049AM | NR1H3 mouse monoclonal antibody, clone OTI1F5 (formerly 1F5), Biotinylated | 100 ul |
$509.00
|
|
| TA805049BM | NR1H3 mouse monoclonal antibody, clone OTI1F5 (formerly 1F5), HRP conjugated | 100 ul |
$509.00
|
|
| TA805049S | NR1H3 mouse monoclonal antibody, clone OTI1F5 (formerly 1F5) | 30 ul |
$200.00
|
|
Citations
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