HSD17B13 Rabbit Monoclonal Antibody [Clone ID: OTIR5C10]
Specifications
| Product Data | |
| Clone Name | OTIR5C10 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000-1:5000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human HSD17B13 produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1.00mg/ml |
| Purification | Purified from cell culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 33.7 kDa |
| Gene Name | hydroxysteroid 17-beta dehydrogenase 13 |
| Database Link | |
| Synonyms | HMFN0376; NIIL497; SCDR9; SDR16C3 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Reviews
Documents
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| FAQs |
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Citations
A phase I/II study of ARO-HSD, an RNA interference therapeutic, for the treatment of non-alcoholic steatohepatitis
Mak, Gane, Schwabe et al
J Hepatol (2022)
Mak, Gane, Schwabe et al
J Hepatol (2022)
Cited by 92
AI Summary: In this study, the OriGene HSD17β13 antibody (TA592047, clone OTIR5C10) was used to quantify hepatic HSD17β13 protein levels, enabling assessment of the therapeutic effects of ARO-HSD in reducing target protein expression in patients with non-alcoholic steatohepatitis.
Snippet: Background & Aims: Loss-of-function HSD17b13 mutations protect against the development of chronic liver disease. HSD17b13 inhibition represents a potential approach Save;04). For protein quantification, specific antibodies against HSD17β13 (OriGene, TA592047, clone OTIR5C10) and vinculin (Cell Signaling Technology, 13901S) were used as primary antibodies and the Ant
Showing 1-1 of 1 papers.
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