HSD17B13 Rabbit Monoclonal Antibody [Clone ID: OTIR5C10]
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTIR5C10 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000-1:5000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human HSD17B13 produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from cell culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 33.7 kDa |
| Gene Name | hydroxysteroid 17-beta dehydrogenase 13 |
| Database Link | |
| Synonyms | HMFN0376; NIIL497; SCDR9; SDR16C3 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
A phase I/II study of ARO-HSD, an RNA interference therapeutic, for the treatment of non-alcoholic steatohepatitis
Mak, Gane, Schwabe et al
J Hepatol (2022)
Mak, Gane, Schwabe et al
J Hepatol (2022)
Cited by 92
AI Summary: In this study, the OriGene HSD17β13 antibody (TA592047, clone OTIR5C10) was used to quantify hepatic HSD17β13 protein levels, enabling assessment of the therapeutic effects of ARO-HSD in reducing target protein expression in patients with non-alcoholic steatohepatitis.
Snippet: Background & Aims: Loss-of-function HSD17b13 mutations protect against the development of chronic liver disease. HSD17b13 inhibition represents a potential approach Save;04). For protein quantification, specific antibodies against HSD17β13 (OriGene, TA592047, clone OTIR5C10) and vinculin (Cell Signaling Technology, 13901S) were used as primary antibodies and the Ant
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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