AMH Rabbit Monoclonal Antibody [Clone ID: OTIR3G5]
Specifications
| Product Data | |
| Clone Name | OTIR3G5 |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA 1:5000-10000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | Recombinant protein (26-560aa) of human AMH produced in HEK303 |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from cell culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Shipping | Blue Ice |
| Predicted Protein Size | 59.17 kDa |
| Gene Name | anti-Mullerian hormone |
| Database Link | |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. provided by RefSeq, Jul 2016 |
| Synonyms | MIF; MIS |
| Reference Data | |
| Protein Categories | Growth Factors, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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