CD4 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Recommended Dilution | WB: 1:5000-1:20000; ELISA: 1:100-1:2000 |
|---|---|
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | DNA immunization. This antibody was made against a protein fragment from the N Terminus Region |
| Buffer | 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0 |
| Concentration | 0.97mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | CD4 molecule |
| Database Link | |
| Background | The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells. |
| Synonyms | CD4mut; IMD79; OKT4D |
| Note | This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane |
| Protein Pathways | Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway |
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