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CD59 Mouse Monoclonal Antibody [Clone ID: OTI2E11]

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SKU
TA507349
CD59 mouse monoclonal antibody, clone OTI2E11 (formerly 2E11)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "CD59 or NM_000611" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2E11
Application WB
Recommended Dilution WB 1:4000
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD59(NP_000602) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 11.6 kDa
Gene Name CD59 molecule (CD59 blood group)
Database Link
Background This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. provided by RefSeq, Jul 2008
Synonyms 1F5; 16.3A5; EJ16; EJ30; EL32; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MIC11; MIN1; MIN2
Reference Data
Protein Categories CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome
Protein Pathways Complement and coagulation cascades, Hematopoietic cell lineage
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Other "OTI2E11" antibodies (4)
SKU Description Size Price
CF507349 Carrier-free (glycerol/BSA-free) CD59 mouse monoclonal antibody, clone OTI2E11 (formerly 2E11) 100 ug
$620.00
TA507349AM CD59 mouse monoclonal antibody, clone OTI2E11 (formerly 2E11), Biotinylated 100 ul
$509.00
TA507349BM CD59 mouse monoclonal antibody, clone OTI2E11 (formerly 2E11), HRP conjugated 100 ul
$509.00
TA507349S CD59 mouse monoclonal antibody, clone OTI2E11 (formerly 2E11) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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