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ERG Mouse Monoclonal Antibody [Clone ID: OTI5F12]

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SKU
TA506077
ERG mouse monoclonal antibody,clone OTI5F12
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "ERG or NM_182918" antibodies

Specifications
Specifications
Product Data
Clone Name OTI5F12
Application IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ERG(NP_891548) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 53.7 kDa
Gene Name ETS transcription factor ERG
Database Link
Background This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan
Synonyms erg-3; p55
Reference Data
Protein Categories Cancer: Sarcoma, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
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Other "OTI5F12" antibodies (6)
SKU Description Size Price
CF506077 Carrier-free (BSA/glycerol-free) ERG mouse monoclonal antibody,clone OTI5F12 100 ug
$620.00
TA506077AM ERG mouse monoclonal antibody,clone 5F12, Biotinylated 100 ul
$509.00
TA506077BM ERG mouse monoclonal antibody,clone 5F12, HRP conjugated 100 ul
$509.00
TA506077S ERG mouse monoclonal antibody,clone OTI5F12 30 ul
$200.00
TA600174 ERG mouse monoclonal capture antibody, validated for ELISA and Luminex assays 100 ug
$458.00
TA700176 ERG biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays 50 ug
$494.00

file-alt Citations

Mapping Isoform Abundance and Interactome of the Endogenous TMPRSS2-ERG Fusion Protein by Orthogonal Immunoprecipitation-Mass Spectrometry Assays
Fu, Rais, Bismar et al
Mol Cell Proteomics (2021)
Cited by 46
AI Summary: OriGene’s anti-ERG antibodies (OriGene Technologies, Rockville, MD) were used as capture antibodies to enrich ERG protein from cell lysates, enabling sensitive detection and quantification of TMPRSS2-ERG fusion isoforms and their interactome in prostate cancer cells.
Snippet: Origene Technologies, Rockville, MD) were used as capture antibodies for the enrichment of ERG protein from cell lysates
IP
Showing 1-1 of 1 papers.
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