ERG Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4H7]
$509.00
5 Days*
Specifications
| Product Data | |
| Clone Name | OTI4H7 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human ERG(NP_891548) produced in HEk293T cell. |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Biotin |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 53.7 kDa |
| Gene Name | ETS transcription factor ERG |
| Database Link | |
| Background | This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan |
| Synonyms | erg-3; p55 |
| Reference Data | |
| Protein Categories | Cancer: Sarcoma, Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4H7" antibodies (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF506076 | Carrier-free (BSA/glycerol-free) ERG mouse monoclonal antibody,clone OTI4H7 | 100 ug |
$620.00
|
|
| TA506076 | ERG mouse monoclonal antibody,clone OTI4H7 | 100 ul |
$447.00
|
|
| TA506076BM | ERG mouse monoclonal antibody,clone 4H7, HRP conjugated | 100 ul |
$509.00
|
|
| TA506076S | ERG mouse monoclonal antibody,clone OTI4H7 | 30 ul |
$200.00
|
|
| TA600175 | ERG mouse monoclonal capture antibody, validated for ELISA and Luminex assays | 100 ug |
$458.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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