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RASA1 Mouse Monoclonal Antibody [Clone ID: OTI4E2]

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SKU
TA505935
RASA1 (GAP ) mouse monoclonal antibody, clone OTI4E2 (formerly 4E2)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "RASA1 or NM_002890" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4E2
Application IF, WB
Recommended Dilution WB 1:2000, IF 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human RASA1(NP_002881) produced in HKE293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 116.2 kDa
Gene Name RAS p21 protein activator 1
Database Link
Background The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues. provided by RefSeq, May 2012
Synonyms CM-AVM; CMAVM; GAP; p120; p120GAP; p120RASGAP; PKWS; RASA; RASGAP
Reference Data
Protein Categories Cancer: Skin, Cytokines, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Axon guidance, MAPK signaling pathway
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Other "OTI4E2" antibodies (4)
SKU Description Size Price
CF505935 Carrier-free (BSA/glycerol-free) RASA1 mouse monoclonal antibody, clone OTI4E2 (formerly 4E2) 100 ug
$620.00
TA505935AM RASA1 mouse monoclonal antibody,clone 4E2, Biotinylated 100 ul
$509.00
TA505935BM RASA1 mouse monoclonal antibody,clone 4E2, HRP conjugated 100 ul
$509.00
TA505935S RASA1 (GAP ) mouse monoclonal antibody, clone OTI4E2 (formerly 4E2) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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